Evidence map›Paper›PMID 19620397›Full record

ReviewGenetics2009

Additive genetic variability and the Bayesian alphabet.

Daniel Gianola, Gustavo de los Campos, William G Hill, Eduardo Manfredi, Rohan Fernando

Abstract readEvaluation StudyReview
In one paragraph

Review in Genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 235 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
235citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

235 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Impact of scale parameter for marker variance prior in some Bayesian whole-genome regression methods.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Article
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175 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel GianolaDepartment of Animal Sciences, University of Wisconsin, Madison, Wisconsin 53706, USA. gianola@ansci.wisc.edu
Gustavo de los Campos
William G Hill
Eduardo Manfredi
Rohan Fernando

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of all available molecular markers in statistical models for prediction of quantitative traits has led to what could be termed a genomic-assisted selection paradigm in animal and plant breeding. This article provides a critical review of some theoretical and statistical concepts in the context of genomic-assisted genetic evaluation of animals and crops. First, relationships between the (Bayesian) variance of marker effects in some regression models and additive genetic variance are examined under standard assumptions. Second, the connection between marker genotypes and resemblance between relatives is explored, and linkages between a marker-based model and the infinitesimal model are reviewed. Third, issues associated with the use of Bayesian models for marker-assisted selection, with a focus on the role of the priors, are examined from a theoretical angle. The sensitivity of a Bayesian specification that has been proposed (called "Bayes A") with respect to priors is illustrated with a simulation. Methods that can solve potential shortcomings of some of these Bayesian regression procedures are discussed briefly.

Indexed as

Bayes TheoremAnimalsGene FrequencyGenetic HeterogeneityGenetic MarkersGenetic VariationModels, GeneticPlantsGenetic Markers

Identifiers

PMID19620397
PMCPMC2746159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.