ArticleGenetics2009
The genetic basis of transgressive ovary size in honeybee workers.
Article in Genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 85 citations in OpenAlex.
- A sterility-associated long noncoding RNA involved in honey bee caste determination and adult queen and worker fertility.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The nature of ant caste allometry.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Examining parent-of-origin effects on transcription and RNA methylation in mediating aggressive behavior in honey bees (Apis mellifera).BMC genomics · 2023Article
- Positive selection in cytochrome P450 genes is associated with gonad phenotype and mating strategy in social bees.Scientific reports · 2023Article
- Societies to genes: can we get there from here?Genetics · 2021Article
- Parent-of-origin effects, allele-specific expression, genomic imprinting and paternal manipulation in social insects.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Attack of the dark clones the genetics of reproductive and color traits of South African honey bees (Apis mellifera spp.).PloS one · 2021Article
- Comparative study of population genomic approaches for mapping colony-level traits.PLoS computational biology · 2020Article
- Review
- Autosomal and Mitochondrial Adaptation Following Admixture: A Case Study on the Honeybees of Reunion Island.Genome biology and evolution · 2018Article
- Do social insects support Haig's kin theory for the evolution of genomic imprinting?Epigenetics · 2017Review
- Integration of lncRNA-miRNA-mRNA reveals novel insights into oviposition regulation in honey bees.PeerJ · 2017Article
- Parent-of-origin effects on genome-wide DNA methylation in the Cape honey bee (Apis mellifera capensis) may be confounded by allele-specific methylation.BMC genomics · 2016Article
- Testing the kinship theory of intragenomic conflict in honey bees (Apis mellifera).Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- The transcriptomic and evolutionary signature of social interactions regulating honey bee caste development.Ecology and evolution · 2015Article
- Article
- Biased Allele Expression and Aggression in Hybrid Honeybees may be Influenced by Inappropriate Nuclear-Cytoplasmic Signaling.Frontiers in genetics · 2015Article
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Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Ovarioles are the functional unit of the female insect reproductive organs and the number of ovarioles per ovary strongly influences egg-laying rate and fecundity. Social evolution in the honeybee (Apis mellifera) has resulted in queens with 200-360 total ovarioles and workers with usually 20 or less. In addition, variation in ovariole number among workers relates to worker sensory tuning, foraging behavior, and the ability to lay unfertilized male-destined eggs. To study the genetic architecture of worker ovariole number, we performed a series of crosses between Africanized and European bees that differ in worker ovariole number. Unexpectedly, these crosses produced transgressive worker phenotypes with extreme ovariole numbers that were sensitive to the social environment. We used a new selective pooled DNA interval mapping approach with two Africanized backcrosses to identify quantitative trait loci (QTL) underlying the transgressive ovary phenotype. We identified one QTL on chromosome 11 and found some evidence for another QTL on chromosome 2. Both QTL regions contain plausible functional candidate genes. The ovariole number of foragers was correlated with the sugar concentration of collected nectar, supporting previous studies showing a link between worker physiology and foraging behavior. We discuss how the phenotype of extreme worker ovariole numbers and the underlying genetic factors we identified could be linked to the development of queen traits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.