SynthesisBMC musculoskeletal disorders2009
Total knee arthroplasty after high tibial osteotomy. A systematic review.
Synthesis in BMC musculoskeletal disorders, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 10 syntheses or guidelines pooled it, 71 citations in OpenAlex.
- High tibial osteotomy versus unicompartmental knee arthroplasty for medial compartment knee osteoarthritis: a comprehensive meta-analysis with patient-specific stratification by age, BMI, and preoperative activity levels.BMC musculoskeletal disorders · 2026Pooled it
- Previous knee surgery increases risks of revision, infection, pain and stiffness after knee replacement arthroplasty: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- High survivorship rate and good clinical outcomes after high tibial osteotomy in patients with radiological advanced medial knee osteoarthritis: a systematic review.Archives of orthopaedic and trauma surgery · 2024Pooled it
- Return to Physical Activity After High Tibial Osteotomy or Unicompartmental Knee Arthroplasty: A Systematic Review and Pooling Data Analysis.The American journal of sports medicine · 2021Pooled it
- Prevalence of femoro-acetabular impingement in non-arthritic patients with hip pain: a meta-analysis.International orthopaedics · 2020Pooled it
- Better clinical outcomes after unicompartmental knee arthroplasty when comparing with high tibial osteotomy.Medicine · 2017Pooled it
- Total knee arthroplasty after failed high tibial osteotomy: a systematic review of open versus closed wedge osteotomy.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2016Pooled it
- What Host Factors Affect Aseptic Loosening After THA and TKA?Clinical orthopaedics and related research · 2015Pooled it
- Osteotomy for treating knee osteoarthritis.The Cochrane database of systematic reviews · 2014Pooled it
- [Changes of patella position after closed and open wedge high tibial osteotomy: review of the literature].Der Orthopade · 2012Pooled it
- Long-term outcomes and factors associated with revision after medial open-wedge high tibial osteotomy in 274 knees: a Kellgren-Lawrence grade-stratified analysis.Knee surgery & related research · 2026Article
- Higher survival rate in total knee arthroplasty after high tibial osteotomy than that after unicompartmental knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- [Are the results of total knee arthroplasty after high tibial osteotomy worse?]Der Orthopade · 2021Article
- Functional Outcome of High Tibial Osteotomy in Patients with Medial Compartment Osteoarthritis Using Dynamic Axial Fixator -a prospective study.Journal of clinical orthopaedics and trauma · 2020Article
- Cartilage Quality (dGEMRIC Index) Following Knee Joint Distraction or High Tibial Osteotomy.Cartilage · 2020Article
- Does a Previous High Tibial Osteotomy (HTO) Influence the Long-term Function or Survival of a Total Knee Arthroplasty (TKA)?The archives of bone and joint surgery · 2018Review
- Single-stage total knee arthroplasty and osteotomy as treatment of secondary osteoarthritis with severe coronal deviation of joint surface due to extra-articular deformity.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2017Article
- Medial compartment knee osteoarthritis: age-stratified cost-effectiveness of total knee arthroplasty, unicompartmental knee arthroplasty, and high tibial osteotomy.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2017Article
- High tibial osteotomy in the ACL-deficient knee with medial compartment osteoarthritis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2016Review
- History of previous knee surgery does not affect the clinical outcomes of primary total knee arthroplasty in an Asian population.Annals of translational medicine · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious osteotomy may compromise subsequent knee replacement, but no guidelines considering knee arthroplasty after prior osteotomy have been developed. We describe a systematic review of non-randomized studies to analyze the effect of high tibial osteotomy on total knee arthroplasty.
methodsA computerized search for relevant studies published up to September 2007 was performed in Medline and Embase using a search strategy that is highly sensitive to find nonrandomized studies. Included were observational studies in which patients had total knee arthroplasty performed after prior high tibial osteotomy. Studies that fulfilled these criteria, were assessed for methodologic quality by two independent reviewers using the critical appraisal of observational studies developed by Deeks and the MINORS instrument. The study characteristics and data on the intervention, follow-up, and outcome measures, were extracted using a pre-tested standardized form. Primary outcomes were: knee range of motion, knee clinical score, and revision surgery. The grade of evidence was determined using the guidelines of the GRADE working group.
resultsOf the 458 articles identified using our search strategy, 17 met the inclusion criteria. Fifteen studies were cohort study with a concurrent control group, one was a historical cohort study and one a case-control study. Nine studies scored 50% or more on both methodological quality assessments. Pooling of the results was not possible due to the heterogeneity of the studies, and our analysis could not raise the overall low quality of evidence. No significant differences between primary total knee arthroplasty and total knee arthroplasty after osteotomy were found for knee range of motion in four out of six studies, knee clinical scores in eight out of nine studies, and revision surgery in eight out of eight studies after a median follow-up of 5 years.
conclusionOur analysis suggests that osteotomy does not compromise subsequent knee replacement. However, the low quality of evidence precludes solid clinical conclusions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.