Evidence map›Paper›PMID 19618913›Full record

ArticleJournal of natural products2009

Aromatic cyclic peroxides and related keto-compounds from the Plakortis sp. component of a sponge consortium.

Emiliano Manzo, M Letizia Ciavatta, Dominique Melck, Peter Schupp, Nicole de Voogd, Margherita Gavagnin

Abstract read
In one paragraph

Article in Journal of natural products, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emiliano ManzoIstituto di Chimica Biomolecolare, CNR, Via Campi Flegrei 34, I 80078-Pozzuoli (Naples), Italy. emanzo@icmib.na.cnr.it
M Letizia Ciavatta
Dominique Melck
Peter Schupp
Nicole de Voogd
Margherita Gavagnin

Funding

TWO DIMENSIONAL NMR OF LIQUID CRYSTALS AND ORIENTED MOLECULESS06GM044796 · NIGMS · UNIVERSITY OF GUAM · PI SCHUPP, PETER J · 1990 to 2010
$3.2M
Univ of Guam/Cancer Res Center of Hawaii PartnershipU56CA096278 · NCI · UNIVERSITY OF GUAM · PI UNDERWOOD, ROBERT A · 2003 to 2008
$2.6M
NCI NIH HHS U56 CA096278NIGMS NIH HHS S06 GM044796
6 · The paper itself

Abstract

Six unreported aromatic compounds, 1-6, were isolated, along with the known compounds dehydrocurcuphenol and manoalide, from a sample of Plakortis sp., which was the main component of a Pacific sponge consortium. The new molecules were chemically characterized by spectroscopic methods. Compounds 1-4 contain a six-membered cyclic peroxide, whereas 5 and 6 display a terminal methyl ketone. The new metabolites were tested for antifungal and antibacterial properties. Compounds 1 and 4 were weakly active against S. aureus.

Indexed as

AnimalsAntifungal AgentsCyclizationDioxanesHumansKetonesMicrobial Sensitivity TestsMolecular StructureNuclear Magnetic Resonance, BiomolecularPeroxidesPoriferaTerpenesAntifungal AgentsDioxanesKetonesmanoalidePeroxidesTerpenes

Identifiers

PMID19618913
PMCPMC2842915

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.