SynthesisClinical orthopaedics and related research2010
How successful are current ankle replacements?: a systematic review of the literature.
Synthesis in Clinical orthopaedics and related research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed, 5 syntheses or guidelines pooled it, 447 citations in OpenAlex.
- Total ankle replacement versus ankle arthrodesis for patients aged 50-85 years with end-stage ankle osteoarthritis: the TARVA RCT.Health technology assessment (Winchester, England) · 2023Pooled it
- Total ankle arthroplasty versus ankle arthrodesis for the treatment of end-stage ankle arthritis: a meta-analysis of comparative studies.International orthopaedics · 2017Pooled it
- The mid-term outcome of total ankle arthroplasty and ankle fusion in rheumatoid arthritis: a systematic review.BMC musculoskeletal disorders · 2013Pooled it
- A systematic review of outcome and failure rate of uncemented Scandinavian total ankle replacement.International orthopaedics · 2011Pooled it
- The sinus tarsi approach in displaced intra-articular calcaneal fractures: a systematic review.International orthopaedics · 2011Pooled it
- [Midterm results following denervation of the ankle].Der Unfallchirurg · 2015Trial
- A Prospective Study on Correlation Between Postural Control Ability and Patient-Reported Outcome Measure After Total Ankle Arthroplasty.Journal of clinical medicine · 2026Article
- Outcomes and associated factors of revision procedures after failed total ankle arthroplasty: a comparative cohort analysis.Archives of orthopaedic and trauma surgery · 2026Article
- Modeling and simulation of a porous mobility total ankle arthroplasty implant: enhancing bone-in growth and reducing micromotion for improved fixation.Journal of orthopaedic surgery and research · 2026Article
- [Our Experience with Trabecular Metal Total Ankle System].Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca · 2026Article
- The Effect of the Modification of Perioperative Anti-Rheumatic Medications on Early Complications After Total Ankle Arthroplasty for Severe Rheumatoid Arthritis.Journal of clinical medicine · 2025Article
- Osteolysis After HINTEGRA Total Ankle Replacement: Radiographic Patterns, Alignment Associations, and Long-Term Outcomes.Foot & ankle orthopaedics · 2025Article
- Is the treatment of ankle osteoarthritis changing over time in Italy? Analysis of temporal trends for fusion and arthroplasty in a population-based study from 2001 to 2022 on the National Hospital Discharge Record database.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025Article
- Statistical shape modeling of shape variability of the human distal tibia: implication for implant design of the tibial component for total ankle replacement.Frontiers in bioengineering and biotechnology · 2025Article
- An evaluation of the total ankle replacement in the modern era: a narrative review.Annals of translational medicine · 2024Review
- Outcome after total ankle replacement or ankle arthrodesis in end-stage ankle osteoarthritis on the basis of german-wide data: a retrospective comparative study over 10 years.BMC musculoskeletal disorders · 2024Article
- Alpha-7 Nicotinic Acetylcholine Receptor Activation Inhibits Trauma Induced Pronociceptive Autoimmune Responses.The journal of pain · 2024Article
- Outcomes of total ankle replacement - Current evidence.Journal of clinical orthopaedics and trauma · 2024Article
- The Cost-Effectiveness of Smoking Cessation Programs for Prevention of Wound Complications Following Total Ankle Arthroplasty: A Break-Even Analysis.Foot & ankle orthopaedics · 2024Article
- Long-Term Survival Analysis of 5619 Total Ankle Arthroplasty and Patient Risk Factors for Failure.Journal of clinical medicine · 2023Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledTotal ankle arthroplasty provides an alternative to arthrodesis for management of ankle arthritis. What is the outcome of total ankle arthroplasty implants currently in use? We conducted a systematic literature search of studies reporting on the outcome of total ankle arthroplasty. We included peer-reviewed studies reporting on at least 20 total ankle arthroplasties with currently used implants, with a minimum followup of 2 years. The Coleman Methodology Score was used to evaluate the quality of the studies. Thirteen Level IV studies of overall good quality reporting on 1105 total ankle arthroplasties (234 Agility, 344 STAR, 153 Buechel-Pappas, 152 HINTEGRA, 98 Salto, 70 TNK, 54 Mobility) were included. Residual pain was common (range, 27%-60%), superficial wound complications occurred in 0% to 14.7%, deep infections occurred in 0% to 4.6% of ankles, and ankle function improved after total ankle arthroplasty. The overall failure rate was approximately 10% at 5 years with a wide range (range, 0%-32%) between different centers. Superiority of an implant design over another cannot be supported by the available data. LEVEL OF EVIDENCE: Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.