Evidence map›Paper›PMID 19617904›Full record

Trial reportBone marrow transplantation2010

Comparison of immune recovery in recipients of unmanipulated vs T-cell-depleted grafts from unrelated donors in a multicenter randomized phase II-III trial (T-cell depletion trial).

C A Keever-Taylor, J E Wagner, N A Kernan, T N Small, S L Carter, J S Thompson, G A Cloud, L S Lamb

Open access · bronzeAbstract readClinical Trial, Phase IIClinical Trial, Phase IIIComparative Study
In one paragraph

Trial report in Bone marrow transplantation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Standard Antithymocyte Globulin Dosing Results in Poorer Outcomes in Overexposed Patients after Ex Vivo CD34Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2019
    Trial
  2. T cell-depleted unrelated donor stem cell transplantation provides favorable disease-free survival for adults with hematologic malignancies.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2011
    Trial
  3. Review
  4. Review
  5. Review
  6. Engineering human peripheral blood stem cell grafts that are depleted of naïve T cells and retain functional pathogen-specific memory T cells.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2014
    Article
  7. Article
  8. NCI, NHLBI/PBMTC first international conference on late effects after pediatric hematopoietic cell transplantation: persistent immune deficiency in pediatric transplant survivors.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2012
    Article
  9. Novel strategies for adoptive therapy following HLA disparate transplants.Best practice & research. Clinical haematology · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

C A Keever-Taylor
J E Wagner
N A Kernan
T N Small
S L Carter
J S Thompson
G A Cloud
L S Lamb
Memorial Sloan Kettering Cancer Center · USEmmes (United States) · USUniversity of Alabama at Birmingham · USUniversity of Kentucky · USUniversity of Minnesota · USUniversity of South Carolina · USVersiti Blood Center of Wisconsin · US

Funding

MEDICAL COORDINATING CENTER FOR T-CELL DEPLETION-N01HB47094-268047094N01HB047094 · HB · EMMES CORPORATION · 1994 to 2005
$189k
THERAPY GROUPS TO STUDY T-CELL DEPLETIONN01HB047097 · HB · UNIVERSITY OF KENTUCKY · PI THOMPSON, JOHN SECORD · 1994 to 2001
–
THERAPY GROUPS TO STUDY T-CELL DEPLETIONN01HB047098 · HB · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI KERNAN, NANCY A. · 1994 to 2000
–
GLUCOSE METABOLISM IN THE EXERCISE TRAINED HEARTR29HL047094 · NHLBI · SYNTEX (USA), INC.-RESEARCH DIVISION · PI STANLEY, WILLIAM C · 1992 to 1995
–
COORD. CTR. FOR CHILDREN'S ACTIVITY TRIAL OF CV HEALTHU01HL047098 · NHLBI · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI FELDMAN, HENRY A · 1991 to 1999
–
NHLBI NIH HHS N01 HB047094NHLBI NIH HHS N01 HB047097NHLBI NIH HHS N01 HB047098NHLBI NIH HHS N01-HB-47094NHLBI NIH HHS N01-HB-47097NHLBI NIH HHS N01-HB-47098NHLBI NIH HHS N01-HB-47195
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lymphocyte DepletionBone Marrow TransplantationDisease-Free SurvivalHumansLiving DonorsLymphocyte CountLymphocyte SubsetsNeoplasmsTime FactorsT-Lymphocytes

Identifiers

PMID19617904
PMCPMC5445657
OpenAlexW2027854546

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.