ArticleThe Journal of experimental biology2009
Thermal activation of escape swimming in post-hatching Xenopus laevis frog larvae.
Article in The Journal of experimental biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 40 citations in OpenAlex.
- Compensation of the effects of temperature on a motor system in the crab,bioRxiv : the preprint server for biology · 2026Article
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- Latitude-Induced and Behaviorally Thermoregulated Variations in Upper Thermal Tolerance of Two Anuran Species.Biology · 2022Article
- A Focal Impact Model of Traumatic Brain Injury inInternational journal of molecular sciences · 2022Article
- The early development and physiology ofJournal of neurophysiology · 2021Article
- Contributions of h- and NaFrontiers in cellular neuroscience · 2021Article
- Antarctic teleosts with and without hemoglobin behaviorally mitigate deleterious effects of acute environmental warming.PloS one · 2021Article
- Reconciling the functions of even-skipped interneurons during crawling, swimming, and walking.Current opinion in physiology · 2019Article
- The constant threat from a non-native predator increases tail muscle and fast-start swimming performance inBiology open · 2017Article
- A method for detailed movement pattern analysis of tadpole startle response.Journal of the experimental analysis of behavior · 2017Article
- Deep-brain photoreception links luminance detection to motor output in Xenopus frog tadpoles.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Short- and long-term consequences of developmental saline stress: impacts on anuran respiration and behaviour.Royal Society open science · 2016Article
- Fast-starting after a breath: air-breathing motions are kinematically similar to escape responses in the catfish Hoplosternum littorale.Biology open · 2014Article
- Modeling human neurodevelopmental disorders in the Xenopus tadpole: from mechanisms to therapeutic targets.Disease models & mechanisms · 2013Review
- Alternative startle motor patterns and behaviors in the larval zebrafish (Danio rerio).Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2012Article
- Activity-dependent expression of Lmx1b regulates specification of serotonergic neurons modulating swimming behavior.Neuron · 2010Article
- How neurons generate behavior in a hatchling amphibian tadpole: an outline.Frontiers in behavioral neuroscience · 2010Article
- Convergence of multisensory inputs in Xenopus tadpole tectum.Developmental neurobiology · 2009Article
- The nitric oxide/cGMP pathway tunes the thermosensitivity of swimming motor patterns in Xenopus laevis tadpoles.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Survival requires the selection of appropriate behavioural responses in the face of danger. With respect to the threat of predation, both the decision to escape and the underlying neuronal mechanisms have been extensively studied, but processes that trigger evasion of abiotic stressors, which are potentially hazardous to survival, are less well understood. Here, we document the interplay between rhythmic locomotory and 'C-start' escape swimming in Xenopus frog larvae when exposed to hyperthermic conditions. As temperature rises, swim cycle frequency increases while swim bout duration decreases, until swimming can no longer be initiated by sensory stimuli. Above a critical higher temperature, more intense sequences of spontaneous high amplitude C-start escape activity occur. Each C-start is followed by a few cycles of fast rhythmic swimming in which activity alternates between the two sides. The initial, high amplitude ventral root burst of an escape sequence propagates rostrocaudally approximately threefold faster than subsequent cycles. The high conduction velocity of this initial burst is consistent with the activation of a Mauthner neuron, one of a pair of giant reticulospinal neurons in fish and amphibians. In support of the involvement of a Mauthner neuron, unilateral lesions of the caudal hindbrain eliminated escape activity on the operated side, but activity remained on the un-operated side. Behaviourally, tadpoles responded to temperature ramps with a sequence of C-start responses in which the body arced through approximately 130 degrees in 22 ms, followed by high frequency swimming. These results suggest that high temperature activates the Mauthner neurons to trigger C-start escape behaviour.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.