Evidence map›Paper›PMID 19616968›Full record

ReviewSeminars in immunology2009

CD40 and the immune response to parasitic infections.

Carlos S Subauste

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Carlos S SubausteDivision of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Cleveland, OH 44106, USA. carlos.subauste@case.edu
Case Western Reserve University · US

Funding

Autophagy and Ocular ToxoplasmosisR01EY018341 · NEI · CASE WESTERN RESERVE UNIVERSITY · PI SUBAUSTE, CARLOS S · 2009 to 2024
$5.0M
CD40 Ligand: Therapy for Opportunistic Pathogens and HIVR01AI048406 · NIAID · UNIVERSITY OF CINCINNATI · PI SUBAUSTE, CARLOS S · 2001 to 2004
$1.0M
NEI NIH HHS EY018341NEI NIH HHS R01 EY018341NIAID NIH HHS AI48406AINIAID NIH HHS R01 AI048406
6 · The paper itself

Abstract

The interaction between CD40 and CD154 regulates many aspects of cellular and humoral immunity. The CD40-CD154 pathway is important for resistance against a variety of parasites. Studies done with these pathogens have provided important insight into the various mechanisms by which this pathway enhances host protection, mechanisms by which pathogens subvert CD40 signaling, conditions in which the CD40-CD154 pathway promotes disease and on modulation of this pathway for immunotherapy.

Indexed as

AnimalsCD40 AntigensCD40 LigandHumansParasitic DiseasesSignal TransductionCD40 AntigensCD40 Ligand

Identifiers

PMID19616968
PMCPMC2758065
OpenAlexW2085644568

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.