Evidence map›Paper›PMID 19616722›Full record

ReviewLancet (London, England)2009

Non-invasive ventilation in acute respiratory failure.

Stefano Nava, Nicholas Hill

4 registry-linked trialsOpen access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Lancet (London, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 212 papers, 18 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
212citing papers in PubMed, 18 pooled it
50.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02240901 nacompletednot on this mapstarted 2016, after this paper: background citation

Effectiveness and Pulmonary Complications of Peri-Operative Laryngeal Mask Airway Used in Elderly Patients(POLMA-EP Trial): a Multi-center Randomized Controlled Clinical Trial

TypeinterventionalSponsorRenJi HospitalRan2016 to 2020Enrolled2,900ConditionsComplications, SurgeryArmsLaryngeal mask airway（LMA）, Endotracheal intubation（ETI）
NCT02918786 naunknown statusnot on this mapstarted 2016, after this paper: background citation

The Efficacy of the Whisperflow CPAP System Versus High Flow Nasal Cannula Oxygen Therapy in Patients at High Risk for Postextubation Failure

TypeinterventionalSponsorRamathibodi HospitalRan2016 to 2017Enrolled140ConditionsRespiratory FailureArmsNasal high-flow, CPAP
NCT03296579 naunknown statusnot on this mapstarted 2018, after this paper: background citation

A Prospective Open Randomized Clinical Trial of Non-invasive Ventilation Versus Standard Therapy for Children Hospitalized With an Acute Exacerbation of Asthma.

TypeinterventionalSponsorUniversity of British ColumbiaRan2018 to 2018Enrolled100ConditionsAsthma Acute, Asthma in ChildrenArmsBiPAP, CPAP, Ipratropium, Magnesium Sulfate, Aminophylline
NCT04026217 suspendednot on this mapstarted 2019, after this paper: background citation

Evaluation of Diaphragmatic Function in Hematological Patients With Acute Hypoxemic Respiratory Failure

TypeobservationalSponsorAzienda Sanitaria-Universitaria Integrata di UdineRan2019 to 2024Enrolled30ConditionsRespiratory Failure, Diaphragm Injury, Ultrasound, Mechanical Ventilation Complication
3 · Its place in the literature

Who cites it

212 citing papers in PubMed, 18 syntheses or guidelines pooled it, 1,001 citations in OpenAlex.

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  14. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD.European respiratory review : an official journal of the European Respiratory Society · 2015
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152 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Stefano NavaRespiratory Intensive Care Unit, Fondazione S Maugeri Istituto Scientifico di Pavia, IRCCS, Pavia, Italy. stefano.nava@fsm.it
Nicholas Hill
Istituti di Ricovero e Cura a Carattere Scientifico · ITTufts Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-invasive mechanical ventilation has been increasingly used to avoid or serve as an alternative to intubation. Compared with medical therapy, and in some instances with invasive mechanical ventilation, it improves survival and reduces complications in selected patients with acute respiratory failure. The main indications are exacerbation of chronic obstructive pulmonary disease, cardiogenic pulmonary oedema, pulmonary infiltrates in immunocompromised patients, and weaning of previously intubated stable patients with chronic obstructive pulmonary disease. Furthermore, this technique can be used in postoperative patients or those with neurological diseases, to palliate symptoms in terminally ill patients, or to help with bronchoscopy; however further studies are needed in these situations before it can be regarded as first-line treatment. Non-invasive ventilation implemented as an alternative to intubation should be provided in an intensive care or high-dependency unit. When used to prevent intubation in otherwise stable patients it can be safely administered in an adequately staffed and monitored ward.

Indexed as

MasksPatient SelectionAcute DiseaseAdultContraindicationsCritical CareEquipment DesignEvidence-Based MedicineHumansImmunocompromised HostIntubation, IntratrachealPersonnel Staffing and SchedulingPositive-Pressure RespirationPulmonary Disease, Chronic ObstructivePulmonary EdemaRespiratory Insufficiency

Identifiers

PMID19616722
PMCPMC7138083
OpenAlexW2119905253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.