Evidence map›Paper›PMID 19616469›Full record

ReviewCurrent opinion in microbiology2009

Nitrosative and oxidative stress responses in fungal pathogenicity.

Alistair J P Brown, Ken Haynes, Janet Quinn

Open access · hybridAbstract readReview
In one paragraph

Review in Current opinion in microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 169 citations in OpenAlex.

  1. Review
  2. Journal of medical microbiology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Response to Oxidative Stress inJournal of fungi (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. ThemSphere · 2023
    Article
  13. Article
  14. Connecting Cryptococcal Meningitis and Gut Microbiome.International journal of molecular sciences · 2023
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Strategies of Pathogens to Escape from NO-Based Host Defense.Antioxidants (Basel, Switzerland) · 2022
    Review
  20. Akt-2 Is a Potential Therapeutic Target for Disseminated Candidiasis.Journal of immunology (Baltimore, Md. : 1950) · 2022
    Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Alistair J P BrownSchool of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK. al.brown@abdn.ac.uk
Ken Haynes
Janet Quinn
Imperial College London · GBNewcastle University · GBUniversity of Aberdeen · GB

Funding

Biotechnology and Biological Sciences Research Council BB/C510391/1Biotechnology and Biological Sciences Research Council BB/D009308/1Biotechnology and Biological Sciences Research Council BB/F000111/1Biotechnology and Biological Sciences Research Council BB/F00513X/1Biotechnology and Biological Sciences Research Council BB/F005210/1Biotechnology and Biological Sciences Research Council BB/F013566/1Wellcome TrustWellcome Trust 080088Wellcome Trust 086048
6 · The paper itself

Abstract

Fungal pathogenicity has arisen in polyphyletic manner during evolution, yielding fungal pathogens with diverse infection strategies and with differing degrees of evolutionary adaptation to their human host. Not surprisingly, these fungal pathogens display differing degrees of resistance to the reactive oxygen and nitrogen species used by human cells to counteract infection. Furthermore, whilst evolutionarily conserved regulators, such as Hog1, are central to such stress responses in many fungal pathogens, species-specific differences in their roles and regulation abound. In contrast, there is a high degree of commonality in the cellular responses to reactive oxygen and nitrogen species evoked in evolutionarily divergent fungal pathogens.

Indexed as

Host-Pathogen InteractionsStress, PhysiologicalAntifungal AgentsFungiHumansModels, BiologicalNitroso CompoundsOxidantsOxidative StressAntifungal AgentsNitroso CompoundsOxidants

Identifiers

PMID19616469
PMCPMC2728829
OpenAlexW1983181251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.