Trial reportJournal of psychosomatic research2009
Frequency and predictors of obstructive sleep apnea among individuals with major depressive disorder and insomnia.
Trial report in Journal of psychosomatic research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00149825 (Combining Antidepressant Medication and Psychotherapy for Insomnia to Improve Depression Outcome), which is not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Combining Antidepressant Medication and Psychotherapy for Insomnia to Improve Depression Outcome
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 103 citations in OpenAlex.
- Obstructive sleep apnea and psychiatric disorders: a systematic review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2015Pooled it
- A randomized controlled trial of cognitive behavioral therapy for insomnia and PAP for obstructive sleep apnea and comorbid insomnia: effects on nocturnal sleep and daytime performance.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Trial
- Trial
- Effects of Obstructive Sleep Apnea on Personality and Temperament: A Cohort and Mendelian Randomization Study.World journal of otorhinolaryngology - head and neck surgery · 2026Article
- The effect of positive airway treatment in women with sleep disordered breathing on the sexual and mental wellbeing of their male partners.Sleep & breathing = Schlaf & Atmung · 2025Article
- Prevalence and risk factors of obstructive sleep apnea in depression: an observational retrospective study.Frontiers in psychiatry · 2025Article
- Assessment of obstructive sleep apnea rate and associated factors among Lebanese adults: a cross-sectional study.Frontiers in public health · 2025Article
- Approach the Patient With Obstructive Sleep Apnea and Obesity.The Journal of clinical endocrinology and metabolism · 2024Article
- Prevalence of obstructive sleep apnea as assessed by polysomnography in psychiatric patients with sleep-related problems.Sleep & breathing = Schlaf & Atmung · 2022Article
- Identifying Obstructive Sleep Apnoea in Patients with Empty Nose Syndrome.Diagnostics (Basel, Switzerland) · 2022Article
- Bidirectional relationships of comorbidity with obstructive sleep apnoea.European respiratory review : an official journal of the European Respiratory Society · 2022Review
- Comorbid Insomnia and Obstructive Sleep Apnea (COMISA): Current Concepts of Patient Management.International journal of environmental research and public health · 2021Review
- Review
- Depressive Symptoms in Comorbid Obstructive Sleep Apnea and Insomnia: An Integrative Review.Western journal of nursing research · 2021Article
- Difference in spectral power density of sleep EEG between patients with simple snoring and those with obstructive sleep apnoea.Scientific reports · 2020Article
- When a patient with depression is feeling sleepy, be aware of sleep apnoea.BMJ case reports · 2018Article
- [Prevalence of sleep-related breathing disorders of inpatients with psychiatric disorders].Der Nervenarzt · 2018Article
- A weight-independent association between atypical antipsychotic medications and obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2018Observational
- Comorbid insomnia and sleep apnea in Veterans with post-traumatic stress disorder.Sleep & breathing = Schlaf & Atmung · 2018Article
- Prevalence and risk factors of moderate to severe obstructive sleep apnea syndrome in major depression: a observational and retrospective study on 703 subjects.BMC pulmonary medicine · 2017Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveDisturbances in sleep continuity are common among individuals with major depressive disorder (MDD) and can impact the course of depression and response to treatment. Several studies have examined depressive symptom severity among sleep-disordered patients with obstructive sleep apnea (OSA). In contrast, little is known about OSA in patients with MDD. The goal of this study was to examine the frequency and predictors of OSA in a sample of individuals with comorbid MDD and insomnia.
methodsParticipants were 51 individuals who enrolled in a treatment study on insomnia and depression, met criteria for MDD and comorbid insomnia, and underwent an overnight polysomnography evaluation. An apnea-hypopnea index >or=15 events per hour was used as a cutoff score for OSA. Regression analyses were conducted to examine clinical and demographic predictors of OSA severity as measured by the apnea-hypopnea index.
resultsThe results revealed that 39% of the sample met criteria for OSA. The OSA group had significantly higher body mass index (BMI) scores and a significantly greater proportion of men. Regression analysis revealed that male sex, older age, and higher BMI were significant predictors of OSA severity. Neither depression severity nor insomnia severity was a significant predictor.
conclusionsThese findings indicate that the frequency of OSA is higher among individuals with comorbid MDD and insomnia than was previously found among people with either MDD or insomnia alone. In addition, previously identified predictors of OSA (male sex, older age, and high BMI) also apply to this population.
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