Evidence map›Paper›PMID 19615731›Full record

ArticleThe Journal of allergy and clinical immunology2009

Does higher body mass index contribute to worse asthma control in an urban population?

Emmanuelle M Clerisme-Beaty, Sabine Karam, Cynthia Rand, Cecilia M Patino, Andrew Bilderback, Kristin A Riekert, Sande O Okelo, Gregory B Diette

Abstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 52 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Clinical characteristics of asthmatic patients with influenza-like illness and risk of severe exacerbations in Mexico.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2016
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Effects of obstructive sleep apnea and gastroesophageal reflux disease on asthma control in obesity.The Journal of asthma : official journal of the Association for the Care of Asthma · 2011
    Article
  11. Article
  12. Reply to Farah.The Journal of allergy and clinical immunology · 2010
    Article
  13. Asthma control, adiposity, and adipokines among inner-city adolescents.The Journal of allergy and clinical immunology · 2010
    Article
  14. Advances in adult asthma diagnosis and treatment in 2009.The Journal of allergy and clinical immunology · 2010
    Review
  15. Obesity and asthma: clinical and laboratory characterization of a common combination.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Emmanuelle M Clerisme-BeatyDepartment of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Sabine Karam
Cynthia Rand
Cecilia M Patino
Andrew Bilderback
Kristin A Riekert
Sande O Okelo
Gregory B Diette
Johns Hopkins University · USAlbert Einstein College of Medicine · USUniversity of Southern California · US

Funding

HOWARD/HOPKINS CENTER FOR REDUCING ASTHMA DISPARTIESU01HL072455 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI RAND, CYNTHIA S · 2002 to 2006
$3.6M
Graduate Training Program in Clinical InvestigationK12RR017627 · NCRR · JOHNS HOPKINS UNIVERSITY · PI ADKINSON, N FRANKLIN · 2003 to 2007
$3.0M
NCRR NIH HHS K12 RR017627NHLBI NIH HHS 5U01HL072455NHLBI NIH HHS U01 HL072455
6 · The paper itself

Abstract

backgroundEpidemiologic findings support a positive association between asthma and obesity.

objectiveDetermine whether obesity or increasing level of body mass index (BMI) are associated with worse asthma control in an ethnically diverse urban population.

methodsCross-sectional assessment of asthma control was performed in patients with asthma recruited from primary care offices by using 4 different validated asthma control questionnaires: the Asthma Control and Communication Instrument (ACCI), the Asthma Control Test (ACT), the Asthma Control Questionnaire (ACQ), and the Asthma Therapy Assessment Questionnaire (ATAQ). Multiple linear regression analysis was performed to evaluate the association between obesity and increasing BMI level and asthma control.

resultsOf 292 subjects with a mean age of 47 years, the majority were women (82%) and African American (67%). There was a high prevalence of obesity with 63%, with only 15% normal weight. The mean score from all 4 questionnaires showed an average suboptimal asthma control (mean score/maximum possible score): ACCI (8.3/19), ACT (15.4/25), ACQ (2.1/6), and ATAQ (1.3/4). Regression analysis showed no association between obesity or increasing BMI level and asthma control using all 4 questionnaires. This finding persisted even after adjusting for FEV(1), smoking status, race, sex, selected comorbid illnesses, and long-term asthma controller use.

conclusionUsing 4 validated asthma control questionnaires, we failed to find an association between obesity and asthma control in an urban population with asthma. Weight loss may not be an appropriate strategy to improve asthma control in this population.

Indexed as

Body Mass IndexAgedAnti-Asthmatic AgentsAsthmaCross-Sectional StudiesFemaleHumansLinear ModelsMaleMiddle AgedObesityPrescription DrugsSpirometrySurveys and QuestionnairesUnited StatesUrban PopulationAnti-Asthmatic AgentsPrescription Drugs

Identifiers

PMID19615731
PMCPMC2733240
OpenAlexW2039942234

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.