ReviewAdvances in genetics2009
Genetic dissection of neural circuits and behavior in Mus musculus.
Review in Advances in genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 36 citations in OpenAlex.
- Cofilin overactivation improves hippocampus-dependent short-term memory.Frontiers in behavioral neuroscience · 2023Article
- Neurobiological insights into twice-exceptionality: Circuits, cells, and molecules.Neurobiology of learning and memory · 2022Article
- Modulating role of serotonergic signaling in sleep and memory.Pharmacological reports : PR · 2022Review
- The role of clock genes in sleep, stress and memory.Biochemical pharmacology · 2021Review
- The phosphodiesterase-4 and glycine transporter-1 inhibitors enhance in vivo hippocampal theta network connectivity and synaptic plasticity, whereas D-serine does not.Translational psychiatry · 2020Article
- A brief period of sleep deprivation causes spine loss in the dentate gyrus of mice.Neurobiology of learning and memory · 2019Article
- Pathways to neurodegeneration: lessons learnt from unbiased genetic screens inJournal of genetics · 2018Review
- Using Temporal Expectation to Assess Auditory Streaming in Mice.Frontiers in behavioral neuroscience · 2018Article
- Article
- Neural Plasticity Is Involved in Physiological Sleep, Depressive Sleep Disturbances, and Antidepressant Treatments.Neural plasticity · 2017Review
- A Laminar Organization for Selective Cortico-Cortical Communication.Frontiers in neuroanatomy · 2017Review
- Compartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Article
- Molecular Genetic Strategies in the Study of Corticohippocampal Circuits.Cold Spring Harbor perspectives in biology · 2015Review
- Impact of adolescent GluA1 AMPA receptor ablation in forebrain excitatory neurons on behavioural correlates of mood disorders.European archives of psychiatry and clinical neuroscience · 2014Article
- Pavlovian contextual and instrumental biconditional discrimination learning in mice.Behavioural brain research · 2013Article
- AKAPS act in a two-step mechanism of memory acquisition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Sleep, plasticity and memory from molecules to whole-brain networks.Current biology : CB · 2013Review
- Pavlovian biconditional discrimination learning in the C57BL/6J mouse.Behavioural processes · 2012Article
- The impact of sleep deprivation on neuronal and glial signaling pathways important for memory and synaptic plasticity.Cellular signalling · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
One of the major challenges in the field of neurobiology is to elucidate the molecular machinery that underlies the formation and storage of memories. For many decades, genetic studies in the fruit fly (Drosophila melanogaster) have provided insight into the role of specific genes underlying memory storage. Although these pioneering studies were groundbreaking, a transition to a mammalian system more closely resembling the human brain is critical for the translation of basic research findings into therapeutic strategies in humans. Because the mouse (Mus musculus) shares the complex genomic and neuroanatomical organization of mammals and there is a wealth of molecular tools that are available to manipulate gene function in mice, the mouse has become the primary model for research into the genetic basis of mammalian memory. Another major advantage of mouse research is the ability to examine in vivo electrophysiological processes, such as synaptic plasticity and neuronal firing patterns during behavior (e.g., the analysis of place cell activity). The focus on mouse models for memory research has led to the development of sophisticated behavioral protocols capable of exploring the role of particular genes in distinct phases of learning and memory formation, which is one of the major accomplishments of the past decade. In this chapter, we will give an overview of several state of the art genetic approaches to study gene function in the mouse brain in a spatially and temporally restricted fashion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.