ArticleJournal of insect science (Online)2009
Evolution of the gene lineage encoding the carbon dioxide receptor in insects.
Article in Journal of insect science (Online), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.
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Who cites it
85 citing papers in PubMed.
- Behavioral determinants of disease transmission by mosquitoes.Current opinion in insect science · 2026Review
- Early hexapod genomes reveal the deep origin of insect gustatory and odorant receptors.Nature communications · 2026Article
- Carbon dioxide drives oviposition inNational science review · 2025Article
- Morphological specializations of mosquito COProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Genetic variation in olfactory pathways associated with host-seeking behavior in natural populations of Anopheles minimus, a primary malaria vector in western Thailand.Parasites & vectors · 2025Article
- The chemosensory world of mosquitoes: olfactory receptors and their role in blocking mosquito-borne disease transmission.Parasites & vectors · 2025Review
- A structural perspective on insect gustatory receptors.Chemical senses · 2025Review
- Food hardness preference reveals multisensory contributions of fly larval gustatory organs in behaviour and physiology.PLoS biology · 2025Article
- Few chemoreceptor genes in the ambrosia beetle Trypodendron lineatum may reflect its specialized ecology.BMC genomics · 2024Article
- Molecular Basis of COInternational journal of molecular sciences · 2024Article
- Evolution of five environmentally responsive gene families in a pine-feeding sawfly,Ecology and evolution · 2023Article
- Temperature-dependent modulation of odor-dependent behavior in three drosophilid fly species of differing thermal preference.Communications biology · 2023Article
- Article
- Identification and expression profile analysis of chemosensory genes in pine needle gall midge,Frontiers in physiology · 2023Article
- The chemosensory system of theFly · 2022Review
- Genome of the hoverfly Eupeodes corollae provides insights into the evolution of predation and pollination in insects.BMC biology · 2022Article
- Identification and Characterization of Chemosensory Receptors in the Pheromone Gland-Ovipositor ofInsects · 2022Article
- Functional olfactory evolution iniScience · 2022Article
- Species-Specificity in Thermopreference and COInsects · 2022Article
- Candidate Chemosensory Genes Identified in the Adult Antennae ofFrontiers in physiology · 2022Article
25 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors.
Funding
Abstract
A heterodimer of the insect chemoreceptors Gr21a and Gr63a has been shown to be the carbon dioxide receptor in Drosophila melanogaster (Meigen) (Diptera: Drosophilidae). Comparison of the genes encoding these two proteins across the 12 available drosophilid fly genomes allows refined definition of their N-termini. These genes are highly conserved, along with a paralog of Gr21a, in the Anopheles gambiae, Aedes aegypti, and Culex pipiens mosquitoes, as well as in the silk moth Bombyx mori and the red flour beetle Tribolium castaneum. In the latter four species we name these three proteins Gr1, Gr2, and Gr3. Intron evolution within this distinctive three gene lineage is considerable, with at least 13 inferred gains and 39 losses. Surprisingly, this entire ancient gene lineage is absent from all other available more basal insect and related arthropod genomes, specifically the honey bee, parasitoid wasp, human louse, pea aphid, waterflea, and blacklegged tick genomes. At least two of these species can detect carbon dioxide, suggesting that they evolved other means to do so.
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