ArticleBiochemistry2009
Single molecule measurements of F1-ATPase reveal an interdependence between the power stroke and the dwell duration.
Article in Biochemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 52 citations in OpenAlex.
- A minimal chemo-mechanical Markov model for rotary catalysis of FNature communications · 2026Article
- Catalytic dwell oscillations complete the FCommunications chemistry · 2025Article
- Eukaryotic yeast VFrontiers in molecular biosciences · 2024Article
- Light, Water, and Melatonin: The Synergistic Regulation of Phase Separation in Dementia.International journal of molecular sciences · 2023Review
- Angle-dependent rotation velocity consistent with ADP release in bacterial FFrontiers in molecular biosciences · 2023Article
- FFrontiers in microbiology · 2022Review
- FFrontiers in microbiology · 2022Review
- pH-dependent 11° FeLife · 2021Article
- The 3 × 120° rotary mechanism ofProceedings of the National Academy of Sciences of the United States of America · 2020Article
- FliIScientific reports · 2020Article
- Rotary catalysis of bovine mitochondrial FProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Method to extract multiple states in FProceedings of the National Academy of Sciences of the United States of America · 2019Article
- A bio-hybrid DNA rotor-stator nanoengine that moves along predefined tracks.Nature nanotechnology · 2018Article
- Elastic coupling power stroke mechanism of the FProceedings of the National Academy of Sciences of the United States of America · 2018Article
- Essential Role of the ε Subunit for Reversible Chemo-Mechanical Coupling in FBiophysical journal · 2018Article
- Protonation-dependent stepped rotation of the F-type ATP synthase c-ring observed by single-molecule measurements.The Journal of biological chemistry · 2017Article
- Power Stroke Angular Velocity Profiles of Archaeal A-ATP Synthase Versus Thermophilic and Mesophilic F-ATP Synthase Molecular Motors.The Journal of biological chemistry · 2016Article
- Theory of single-molecule controlled rotation experiments, predictions, tests, and comparison with stalling experiments in F1-ATPase.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- The effect of medium viscosity on kinetics of ATP hydrolysis by the chloroplast coupling factor CF1.Photosynthesis research · 2016Article
- Theory for rates, equilibrium constants, and Brønsted slopes in F1-ATPase single molecule imaging experiments.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Increases in the power stroke and dwell durations of single molecules of Escherichia coli F(1)-ATPase were measured in response to viscous loads applied to the motor and inhibition of ATP hydrolysis. The load was varied using different sizes of gold nanorods attached to the rotating gamma subunit and/or by increasing the viscosity of the medium using PEG-400, a noncompetitive inhibitor of ATPase activity. Conditions that increase the duration of the power stroke were found to cause 20-fold increases in the length of the dwell. These results suggest that the order of hydrolysis, product release, and substrate binding may change as the result of external load on the motor or inhibition of hydrolysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.