ArticleTechniques in coloproctology2009
Young-age onset of colorectal cancer in Israel.
Article in Techniques in coloproctology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Early-onset colorectal cancer: A review of current knowledge.World journal of gastroenterology · 2023Review
- The Effect of 5-Fluorouracil on the Adhesion Process in Patients Operated on for Colorectal Cancer.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Gastrointestinal Adenocarcinoma Incidence and Survival Trends in South Australia, 1990-2017.Cancers · 2022Article
- Impact of age and mismatch repair status on survival in colorectal cancer.Cancer medicine · 2017Article
- Octogenarian patients with colorectal cancer: Characterizing an emerging clinical entity.World journal of gastroenterology · 2017Article
- Colorectal cancer in young patients: is it a distinct clinical entity?International journal of clinical oncology · 2016Article
- Effect of Age on Survival Outcome in Operated and Non-Operated Patients with Colon Cancer: A Population-Based Study.PloS one · 2016Article
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- Association of age with survival in patients with metastatic colorectal cancer: analysis from the ARCAD Clinical Trials Program.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2014Article
- Pathological features and survival outcomes of young patients with operable colon cancer: are they homogeneous?PloS one · 2014Article
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- Young colorectal carcinoma patients do not have a poorer prognosis: a comparative review of 2,426 cases.Techniques in coloproctology · 2013Article
- Clinical characteristics and prognosis of young patients with colorectal cancer in Eastern China.World journal of gastroenterology · 2013Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe study was conducted to investigate the differences in clinical-pathological, ethnic, and demographic presentations and the expression of mismatch repair proteins in a cohort of young-onset (</=50 years) versus late-onset Israeli patients (>50 years) with colorectal cancer. MATERIALS AND
methodsClinical, demographic, and histopathological data of patients with colorectal cancer were collected retrospectively from medical records and pathology reports.
resultsNinety patients, 50 years of age or younger with a mean age of 42 years were compared with a group of 190 patients above 50 years of 50 (see Table 1). Sixty percent of the young-onset patients were females, compared to 40% in the older age group (P = 0.02). Twenty-one percent of the young-onset patients were Arabs as compared to 2% of older-onset patients (P = 0.001). Younger patients displayed a higher percentage of mucinous cancers and a higher percentage of diagnosis at an advanced stage of disease; 40% of young-onset versus 31% of older-onset patients presented Duke's stages C and D (P = 0.02).
conclusionsYounger age of onset colorectal cancer in our cohort of Israeli patients is associated with higher percentage of Arab patients, mucinous cancers, female gender, and advanced stage at diagnosis.
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