ArticleJournal of visualized experiments : JoVE2009
Dissecting the non-human primate brain in stereotaxic space.
Article in Journal of visualized experiments : JoVE, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Mapping the primate thalamus: systematic approach to analyze the distribution of subcortical neuromodulatory afferents.Brain structure & function · 2023Article
- Dose-Related Reduction in Hippocampal Neuronal Populations in Fetal Alcohol Exposed Vervet Monkeys.Brain sciences · 2022Article
- Atlas of the Striatum and Globus Pallidus in the Tree Shrew: Comparison with Rat and Mouse.Neuroscience bulletin · 2018Article
- Alcohol and Apoptosis: Friends or Foes?Biomolecules · 2015Article
- Hippocampal neuron populations are reduced in vervet monkeys with fetal alcohol exposure.Developmental psychobiology · 2015Article
- Controlling feeding behavior by chemical or gene-directed targeting in the brain: what's so spatial about our methods?Frontiers in neuroscience · 2013Review
- Reduced soma size of the M-neurons in the lateral geniculate nucleus following foetal alcohol exposure in non-human primates.Experimental brain research · 2010Article
- Brain banking: making the most of your research specimens.Journal of visualized experiments : JoVE · 2009Article
- Knowing what counts: unbiased stereology in the non-human primate brain.Journal of visualized experiments : JoVE · 2009Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of non-human primates provides an excellent translational model for our understanding of developmental and aging processes in humans(1-6). In addition, the use of non-human primates has recently afforded the opportunity to naturally model complex psychiatric disorders such as alcohol abuse(7). Here we describe a technique for blocking the brain in the coronal plane of the vervet monkey (Chlorocebus aethiops sabeus) in the intact skull in stereotaxic space. The method described here provides a standard plane of section between blocks and subjects and minimizes partial sections between blocks. Sectioning a block of tissue in the coronal plane also facilitates the delineation of an area of interest. This method provides manageable sized blocks since a single hemisphere of the vervet monkey yields more than 1200 sections when slicing at 50 microm. Furthermore by blocking the brain into 1cm blocks, it facilitates penetration of sucrose for cyroprotection and allows the block to be sliced on a standard cryostat.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.