Evidence map›Paper›PMID 19608958›Full record

ArticleAmerican journal of public health2010

Explaining the decrease in coronary heart disease mortality in Italy between 1980 and 2000.

Luigi Palmieri, Kathleen Bennett, Simona Giampaoli, Simon Capewell

Abstract read
In one paragraph

Article in American journal of public health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  5. Cardiovascular Disease in Saudi Arabia: Facts and the Way Forward.Journal of the Saudi Heart Association · 2023
    Review
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  19. Time Trends of High Blood Pressure Prevalence, Awareness and Control in the Italian General Population : Surveys of the National Institute of Health.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luigi PalmieriNational Centre of Epidemiology, Surveillance, and Promotion of Health, National Institutes of Health, 00162 Rome, Italy. luigi.palmieri@iss.it
Kathleen Bennett
Simona Giampaoli
Simon Capewell

Funding

Medical Research Council G0500920
6 · The paper itself

Abstract

objectivesWe examined the extent to which the decrease in coronary heart disease (CHD) mortality rates in Italy could be explained by changes in cardiovascular risk factors versus the use of medical and surgical treatments.

methodsWe used a validated model to combine data on changes in risk factors and uptake and effectiveness of cardiac treatments among adult men and women in Italy between 1980 and 2000. Data sources included results of published trials, meta-analyses, official statistics, longitudinal studies, and national surveys. The difference between observed and expected CHD deaths in 2000 was partitioned among treatments and risk factors.

resultsFrom 1980 to 2000, the age-adjusted CHD mortality rate in Italy fell among persons aged 25 to 84 years, resulting in 42 930 fewer CHD deaths in 2000. Approximately 40% of this decrease was attributed to treatments and 55% to changes in risk factors.

conclusionsOver half of the CHD mortality fall in Italy between 1980 and 2000 was attributable to reductions in major risk factors, mainly cholesterol and blood pressure, and less than half to evidence-based medical therapies. These results are becoming increasingly important, both for understanding past trends and for planning future prevention and treatment strategies.

Indexed as

AdultAgedAged, 80 and overAge FactorsBlood PressureBody Mass IndexCholesterolCoronary DiseaseFemaleHospitalizationHumansItalyMaleMiddle AgedModels, TheoreticalMortalityCholesterol

Identifiers

PMID19608958
PMCPMC2836342

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.