Evidence map›Paper›PMID 19607875›Full record

ArticleBio Systems2009

Construction of a DNA nano-object directly demonstrates computation.

Gang Wu, Natasha Jonoska, Nadrian C Seeman

Abstract read
In one paragraph

Article in Bio Systems, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Molecular ping-pong Game of Life on a two-dimensional DNA origami array.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2015
    Article
  2. Strong bending of the DNA double helix.Nucleic acids research · 2013
    Review
  3. Article
  4. Article
  5. Article
  6. Bending of short DNA helices.Artificial DNA, PNA & XNA
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gang WuDepartment of Chemistry, New York University, New York, NY 10003, USA. gw335@nyu.edu
Natasha Jonoska
Nadrian C Seeman

Funding

Physical Chemistry of Recombinational IntermediatesR37GM029554 · NIGMS · NEW YORK UNIVERSITY · PI SEEMAN, NADRIAN C. · 2005 to 2012
$2.7M
PHYSICAL CHEMISTRY OF RECOMBINATIONAL INTERMEDIATESR01GM029554 · NIGMS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI SEEMAN, NADRIAN C. · 1985 to 2004
$1.4M
NIGMS NIH HHS GM-29554NIGMS NIH HHS R01 GM029554NIGMS NIH HHS R37 GM029554
6 · The paper itself

Abstract

We demonstrate a computing method in which a DNA nano-object representing the solution of a problem emerges as a result of self-assembly. We report an experiment in which three-vertex colorability for a six-vertex graph with nine edges is solved by constructing a DNA molecule representing the colored graph itself. Our findings show that computation based on "shape processing" is a viable alternative to symbol processing when computing by molecular self-assembly.

Indexed as

Computer SimulationModels, MolecularComputational BiologyComputer GraphicsDNADNA, CircularDNA, Single-StrandedNanostructuresNucleic Acid ConformationDNADNA, CircularDNA, Single-Stranded

Identifiers

PMID19607875
PMCPMC2763046

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.