Evidence map›Paper›PMID 19607693›Full record

SynthesisBMC ophthalmology2009

Effectiveness of screening preschool children for amblyopia: a systematic review.

Christine Schmucker, Robert Grosselfinger, Rob Riemsma, Gerd Antes, Stefan Lange, Wolf Lagrèze, Jos Kleijnen

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in BMC ophthalmology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Amblyopia.BMJ clinical evidence · 2011
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Causes of Reduced Vision in Australian Children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  7. Article
  8. Article
  9. A situational analysis of clinical refraction services in the capital city of the Maldives.Medical hypothesis, discovery & innovation ophthalmology journal · 2021
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. [Possibilities and limitations of amblyopia screening with auto-refractometers].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2016
    Article
  15. Article
  16. Amblyopia Prevention Screening Program in Northwest Iran (Ardabil).International journal of preventive medicine · 2016
    Article
  17. Article
  18. Article
  19. Childhood vision screening in Canada: public health evidence and practice.Canadian journal of public health = Revue canadienne de sante publique
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Christine SchmuckerDepartment of Medical Biometry and Statistics (German Cochrane Center), Institute of Medical Biometry and Medical Informatics, University Medical Center, Freiburg, Germany. schmucker@cochrane.de
Robert Grosselfinger
Rob Riemsma
Gerd Antes
Stefan Lange
Wolf Lagrèze
Jos Kleijnen
Institute for Quality and Efficiency in Health Care · DEKleijnen Systematic Reviews (United Kingdom) · GBUniversity Medical Center Freiburg · DEZimmer Biomet (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmblyopia and amblyogenic factors like strabismus and refractive errors are the most common vision disorders in children. Although different studies suggest that preschool vision screening is associated with a reduced prevalence rate of amblyopia, the value of these programmes is the subject of a continuing scientific and health policy discussion. Therefore, this systematic review focuses on the question of whether screening for amblyopia in children up to the age of six years leads to better vision outcomes.

methodsTen bibliographic databases were searched for randomised controlled trials, non-randomised controlled trials and cohort studies with no limitations to a specific year of publication and language. The searches were supplemented by handsearching the bibliographies of included studies and reviews to identify articles not captured through our main search strategy.

resultsFive studies met the inclusion criteria. Of these, three studies suggested that screening is associated with an absolute reduction in the prevalence of amblyopia between 0.9% and 1.6% (relative reduction: between 45% and 62%). However, the studies showed weaknesses, limiting the validity and reliability of their findings. The main limitation was that studies with significant results considered only a proportion of the originally recruited children in their analysis. On the other hand, retrospective sample size calculation indicated that the power based on the cohort size was not sufficient to detect small changes between the groups. Outcome parameters such as quality of life or adverse effects of screening have not been adequately investigated in the literature currently available.

conclusionPopulation based preschool vision screening programmes cannot be sufficiently assessed by the literature currently available. However, it is most likely that the present systematic review contains the most detailed description of the main limitations in current available literature evaluating these programmes. Therefore, future research work should be guided by the findings of this publication.

Indexed as

Program EvaluationVision ScreeningAmblyopiaChild, PreschoolEpidemiologic StudiesHumansOutcome Assessment, Health Care

Identifiers

PMID19607693
PMCPMC2731050
OpenAlexW2065041441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.