ArticleBMC genomics2009
Application of chicken microarrays for gene expression analysis in other avian species.
Article in BMC genomics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 27 citations in OpenAlex.
- Age-Dependent Lethality in Ducks Caused by Highly Pathogenic H5N6 Avian Influenza Virus.Viruses · 2020Article
- Dynamic Changes in the Splenic Transcriptome of Chickens during the Early Infection and Progress of Marek's Disease.Scientific reports · 2017Article
- aCGH Analysis to Estimate Genetic Variations among Domesticated Chickens.BioMed research international · 2016Article
- DNA microarray global gene expression analysis of influenza virus-infected chicken and duck cells.Genomics data · 2015Article
- Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses.Veterinary research · 2014Article
- Article
- Transcriptional analysis of the innate immune response of ducks to different species-of-origin low pathogenic H7 avian influenza viruses.Virology journal · 2013Article
- Article
- Quail Genomics: a knowledgebase for Northern bobwhite.BMC bioinformatics · 2010Article
- From raw materials to validated system: the construction of a genomic library and microarray to interpret systemic perturbations in Northern bobwhite.Physiological genomics · 2010Article
- Introduction to the proceedings of the Avian Genomics and Gene Ontology Annotation Workshop.BMC genomics · 2009Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWith the threat of emerging infectious diseases such as avian influenza, whose natural hosts are thought to be a variety of wild water birds including duck, we are armed with very few genomic resources to investigate large scale immunological gene expression studies in avian species. Multiple options exist for conducting large gene expression studies in chickens and in this study we explore the feasibility of using one of these tools to investigate gene expression in other avian species.
resultsIn this study we utilised a whole genome long oligonucleotide chicken microarray to assess the utility of cross species hybridisation (CSH). We successfully hybridised a number of different avian species to this array, obtaining reliable signals. We were able to distinguish ducks that were infected with avian influenza from uninfected ducks using this microarray platform. In addition, we were able to detect known chicken immunological genes in all of the hybridised avian species.
conclusionCross species hybridisation using long oligonucleotide microarrays is a powerful tool to study the immune response in avian species with little available genomic information. The present study validated the use of the whole genome long oligonucleotide chicken microarray to investigate gene expression in a range of avian species.
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