ArticleDrug delivery2009
Polyelectrolyte-coated alginate microspheres as drug delivery carriers for dexamethasone release.
Article in Drug delivery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Blood glucose self-monitoring with a long-term subconjunctival glucose sensor.Journal of diabetes science and technology · 2013Trial
- Design and Evaluation of Alginate-Based Hydrogels for Controlled Release of Cationic and Anionic Model Compounds.Gels (Basel, Switzerland) · 2026Article
- Exploring the role of mesoporous silica nanoparticle in the development of novel drug delivery systems.Drug delivery and translational research · 2022Review
- Development of Theophylline Microbeads Using Pregelatinized Breadfruit Starch (Advanced pharmaceutical bulletin · 2019Article
- Optimizing the Bioavailability of Subcutaneously Administered Biotherapeutics Through Mechanochemical Drivers.Pharmaceutical research · 2017Review
- Novel nanoformulation to mitigate co-effects of drugs of abuse and HIV-1 infection: towards the treatment of NeuroAIDS.Journal of neurovirology · 2017Article
- Delivery of dexamethasone from bioactive nanofiber matrices stimulates odontogenesis of human dental pulp cells through integrin/BMP/mTOR signaling pathways.International journal of nanomedicine · 2016Article
- Sustained-release nanoART formulation for the treatment of neuroAIDS.International journal of nanomedicine · 2015Article
- The potential of magneto-electric nanocarriers for drug delivery.Expert opinion on drug delivery · 2014Review
- The effect of polymer and CaClProgress in biomaterials · 2013Article
- "Smart tattoo" glucose biosensors and effect of coencapsulated anti-inflammatory agents.Journal of diabetes science and technology · 2011Article
- Marine polysaccharides in pharmaceutical applications: an overview.Marine drugs · 2010Review
- Bacterial components as naturally inspired nano-carriers for drug/gene delivery and immunization: Set the bugs to work?Biotechnology advancesReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Alginate microspheres loaded with dexamethasone were prepared by the droplet generator technique. Important parameters affecting drug release, including initial drug content, the type of polyelectrolyte coating, and a combination of different ratios of coated and uncoated microspheres were investigated to achieve in vitro dexamethasone delivery with approximately zero order release kinetics, releasing up to 100% of entrapped drug within 1 month, wherein dexamethasone released at a steady rate of 4.83 microg/day after an initial burst release period. These findings imply that these polyelectrolyte-coated alginate microspheres show promise as release systems to improve biocompatibility and prolong lifetime of implantable glucose sensors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.