ArticleIEEE transactions on bio-medical engineering2009
Multiple types of movement-related information encoded in hindlimb/trunk cortex in rats and potentially available for brain-machine interface controls.
Article in IEEE transactions on bio-medical engineering, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 41 citations in OpenAlex.
- Neural Network Connection Characteristics Between Motor Cortex and Spinal Cord During Rat Bipedal Walking.CNS neuroscience & therapeutics · 2026Article
- Dynamic Changes in Hindlimb Motor Cortex Neurons during Simulated Weightlessness Revealed by Miniature 2-Photon Microscopy.Research (Washington, D.C.) · 2025Article
- Article
- Time-Varying Functional Connectivity of Rat Brain during Bipedal Walking on Unexpected Terrain.Cyborg and bionic systems (Washington, D.C.) · 2023Article
- Decoding Bilateral Hindlimb Kinematics From Cat Spinal Signals Using Three-Dimensional Convolutional Neural Network.Frontiers in neuroscience · 2022Article
- The Future of Neuroscience: Flexible and Wireless Implantable Neural Electronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Faster Gait Speeds Reduce Alpha and Beta EEG Spectral Power From Human Sensorimotor Cortex.IEEE transactions on bio-medical engineering · 2020Article
- Decoding Movement From Electrocorticographic Activity: A Review.Frontiers in neuroinformatics · 2019Review
- Low-Dimensional Motor Cortex Dynamics Preserve Kinematics Information During Unconstrained Locomotion in Nonhuman Primates.Frontiers in neuroscience · 2019Article
- Implantable Neural Probes for Brain-Machine Interfaces - Current Developments and Future Prospects.Experimental neurobiology · 2018Review
- Brain-controlled modulation of spinal circuits improves recovery from spinal cord injury.Nature communications · 2018Article
- Engagement of the Rat Hindlimb Motor Cortex across Natural Locomotor Behaviors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Teaching Adult Rats Spinalized as Neonates to Walk Using Trunk Robotic Rehabilitation: Elements of Success, Failure, and Dependence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Combined motor cortex and spinal cord neuromodulation promotes corticospinal system functional and structural plasticity and motor function after injury.Experimental neurology · 2016Article
- Adaptation to elastic loads and BMI robot controls during rat locomotion examined with point-process GLMs.Frontiers in systems neuroscience · 2015Article
- Dissociating movement from movement timing in the rat primary motor cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Electronic bypass of spinal lesions: activation of lower motor neurons directly driven by cortical neural signals.Journal of neuroengineering and rehabilitation · 2014Article
- A pelvic implant orthosis in rodents, for spinal cord injury rehabilitation, and for brain machine interface research: construction, surgical implantation and validation.Journal of neuroscience methods · 2014Article
- A brain-machine-muscle interface for restoring hindlimb locomotion after complete spinal transection in rats.PloS one · 2014Article
- Decoding hindlimb movement for a brain machine interface after a complete spinal transection.PloS one · 2012Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Brain-machine interface (BMI) systems hold the potential to return lost functions to patients with motor disorders. To date, most efforts in BMI have concentrated on decoding neural activity from forearm areas of cortex to operate a robotic arm or perform other manipulation tasks. Efforts have neglected the locomotion functions of hindlimb/trunk cortex. However, the role of cortex in hindlimb locomotion of intact rats, which are often model systems for BMI testing, is usually considered to be small. Thus, the quality of representations of locomotion available in this area was uncertain. We designed a new rodent BMI system, and tested decoding of the kinematics of trunk and hindlimbs during locomotion using linear regression. Recordings were made from the motor cortex of the hindlimb/trunk area in rats using arrays of six tetrodes (24 channels total). We found that multiple movement-related variables could be decoded simultaneously during locomotion, ranging from the proximal robot/pelvis attachment point, and the distal toe position, through hindlimb joint angles and limb endpoint in a polar coordinate system. Remarkably, the best reconstructed motion parameters were the more proximal kinematics, which might relate to global task variables. The pelvis motion was significantly better reconstructed than any other motion features.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.