Evidence map›Paper›PMID 19603201›Full record

ArticleClinical oral investigations2010

Bisphosphonate-related osteonecrosis of the jaw: clinical correlations with computerized tomography presentation.

Sharon Elad, Moshe J Gomori, Noa Ben-Ami, Silvina Friedlander-Barenboim, Eran Regev, Towy S Lazarovici, Noam Yarom

Abstract read
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In one paragraph

Article in Clinical oral investigations, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Application of navigation system during surgery for medication-related osteonecrosis of the jaw.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2025
    Article
  4. Article
  5. Osteonecrosis of the Jaw.Dentistry journal · 2023
    Review
  6. Article
  7. Review
  8. Article
  9. Pain characteristics in medication-related osteonecrosis of the jaws.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  10. Review
  11. Article
  12. Article
  13. Periapical disease and bisphosphonates induce osteonecrosis of the jaws in mice.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2013
    Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sharon EladDepartment of Oral Medicine, Hebrew University-Hadassah School of Dental Medicine, Jerusalem, Israel. sharon.elad@ekmd.huji.ac.il
Moshe J Gomori
Noa Ben-Ami
Silvina Friedlander-Barenboim
Eran Regev
Towy S Lazarovici
Noam Yarom

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to correlate clinical and computerized tomography (CT) features of bisphosphonate-related osteonecrosis of the jaws (BRONJ). All ONJ patients for whom there was complete CT scan imaging were eligible. Selected clinical parameters retrieved from their medical records were analyzed for correlation with CT parameters. The clinical presentation of BRONJ was supported by findings in CT imaging in 78.3%. The lesion's size on CT correlated with the presence of purulent secretion (p = 0.03). When sequestrum was present, the median lesion's size on CT was relatively big (28 mm, range 21-43 mm). The mandibular canal cortex was never breached. CT has reasonable detection competence for diagnosing BRONJ. Purulent secretion indicates the likelihood that a more extensive involvement will be displayed on CT. A large lesion on CT should raise the index of suspicion for sequestrum. The CT appearance of a continuous cortex of the mandibular canal may serve as a differential parameter between BRONJ and metastasis to the jaw.

Indexed as

AgedAged, 80 and overBone Density Conservation AgentsDiphosphonatesFemaleHumansJaw DiseasesMaleMiddle AgedOsteonecrosisTomography, X-Ray ComputedBone Density Conservation AgentsDiphosphonates

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.