ArticleMaterials Research Society symposia proceedings. Materials Research Society2009
Mapping the Micromechanical Properties of Cryo-sectioned Aortic Tissue with Scanning Acoustic Microscopy.
Article in Materials Research Society symposia proceedings. Materials Research Society, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- Biomechanical changes after repeated collagen cross-linking on human corneas assessed in vitro using scanning acoustic microscopy.Investigative ophthalmology & visual science · 2014Trial
- A pilot study of scanning acoustic microscopy as a tool for measuring arterial stiffness in aortic biopsies.Artery research · 2016Article
- Tissue stiffness dictates development, homeostasis, and disease progression.Organogenesis · 2015Review
- Biomechanical properties of human corneas following low- and high-intensity collagen cross-linking determined with scanning acoustic microscopy.Investigative ophthalmology & visual science · 2013Article
- Localised micro-mechanical stiffening in the ageing aorta.Mechanisms of ageing and development · 2011Article
- Characterizing the elastic properties of tissues.Materials today (Kidlington, England) · 2011Article
- Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer.Disease models & mechanisms · 2011Article
- Quantifying Micro-mechanical Properties of Soft Biological Tissues with Scanning Acoustic Microscopy.Materials Research Society symposia proceedings. Materials Research Society · 2011Article
- Tissue section AFM: In situ ultrastructural imaging of native biomolecules.Matrix biology : journal of the International Society for Matrix Biology · 2010Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Although the gross mechanical properties of ageing tissues have been extensively documented, biological tissues are highly heterogeneous and little is known concerning the variation of micro-mechanical properties within tissues. Here, we use Scanning Acoustic Microscopy (SAM) to map the acoustic wave speed (a measure of stiffness) as a function of distance from the outer adventitial layer of cryo-sectioned ferret aorta. With a 400 MHz lens, the images of the aorta samples matched those obtained following chemical fixation and staining of sections which were viewed with fluorescence microscopy. Quantitative analysis was conducted with a frequency scanning or V(f) technique by imaging the tissue from 960 MHz to 1.1 GHz. Undulating acoustic wave speed (stiffness) distributions corresponded with elastic fibre locations in the tissue; there was a decrease in wave speed of around 40 ms(-1) from the adventitia (outer layer) to the intima (innermost).
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.