Evidence map›Paper›PMID 19602663›Full record

ArticleCanadian family physician Medecin de famille canadien2009

Drug management for hypertension in type 2 diabetes in family practice.

Wayne Putnam, Farokh Buhariwalla, Kendrick Lacey, Mary Goodfellow, Rose Anne Goodine, Jennifer Hall, Ian Macdonald, Michael Murray, Preston Smith, Fred Burge and 2 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Canadian family physician Medecin de famille canadien, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Hypertension and the family physician.Canadian family physician Medecin de famille canadien · 2009
    Article
  6. Hypertension management by family physicians: is it time to pat ourselves on the back?Canadian family physician Medecin de famille canadien · 2009
    Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Wayne PutnamDepartment of Family Medicine, Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, NS B3H 2E2. wayne.putnam@dal.ca
Farokh Buhariwalla
Kendrick Lacey
Mary Goodfellow
Rose Anne Goodine
Jennifer Hall
Ian Macdonald
Michael Murray
Preston Smith
Fred Burge
Nandini Natarajan
Beverley Lawson
Dalhousie University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the number and classes of antihypertensive medications prescribed to patients with type 2 diabetes in community family practices, and to estimate the aggressiveness or "dosage intensity" of prescribing for hypertension in these situations.

designPractice-based, cross-sectional observational study.

settingSeventeen rural and urban family practices in the Maritime Family Practice Research Network in Nova Scotia, New Brunswick, and Prince Edward Island.

participantsA total of 670 patients with type 2 diabetes, ranging from 25 to 92 years of age.

main outcome measuresNumber, classes, and combinations of classes of antihypertensive medications prescribed, as well as an index of each medication's dosage intensity.

resultsAlmost 80% of patients studied had hypertension. Participants with hypertension were taking an average of 2.5 medications, and 47.6% were taking 3 or more antihypertensive medications, but only 27.1% reached target blood pressure values of less than 130/80 mm Hg. Older patients took more antihypertensive medications, but there were no differences by sex. More than 90% were taking angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, 66% were taking diuretics, 41% were taking beta-blockers, and 38% were taking calcium channel blockers. We cannot describe the sequence in which antihypertensive medication classes were added, but analysis of patients taking multiple drug classes suggests that most patients were started on angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, followed by diuretics, beta-blockers, or calcium channel blockers. The most commonly used medications were prescribed at higher than two-thirds the maximum dose effective for hypertension.

conclusionHypertension is very common among family practice patients with type 2 diabetes; of those patients, few reach target blood pressures. Practice-based strategies to increase dosing and number of medications prescribed might be required.

Indexed as

AdultAgedAged, 80 and overAge DistributionAntihypertensive AgentsCanadaCohort StudiesCross-Sectional StudiesDiabetes Mellitus, Type 2Dose-Response Relationship, DrugFamily PracticeFemaleHealth Care SurveysHumansHypertensionMaleAntihypertensive Agents

Identifiers

PMID19602663
PMCPMC2718608
OpenAlexW2123894847

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.