ReviewNature reviews. Gastroenterology & hepatology2009
Endoscopy for upper gastrointestinal bleeding: how urgent is it?
Review in Nature reviews. Gastroenterology & hepatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Does Early Endoscopy Affect the Clinical Outcomes of Patients with Acute Nonvariceal Upper Gastrointestinal Bleeding? A Systematic Review and Meta-Analysis.Gut and liver · 2023Pooled it
- [Guidelines for Non-variceal Upper Gastrointestinal Bleeding].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2020Guideline
- Impact of Urgent Versus Early Endoscopy on Outcomes in Acute Upper Gastrointestinal Bleeding: A Retrospective Study.Canadian journal of gastroenterology & hepatology · 2025Article
- Article
- The Time of Endoscopy for Nonvariceal Upper Gastrointestinal Bleeding: An Observational Study.The Korean journal of helicobacter and upper gastrointestinal research · 2024Article
- Endoscopy for acute upper gastrointestinal bleeding: a protocol for systematic review and network meta-analysis of randomized controlled trials.International journal of surgery protocols · 2024Article
- Emergency Endoscopic Interventions in Acute Upper Gastrointestinal Bleeding: A Cohort Study.Diagnostics (Basel, Switzerland) · 2023Article
- How Can Patient's Risk Dictate the Timing of Endoscopy in Upper Gastrointestinal Bleeding?GE Portuguese journal of gastroenterology · 2022Article
- Early Identification of High-Risk Factors for Upper Gastrointestinal Bleeding.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Relationship between angiography timing and angiographic visualization of extravasation in patients with acute non-variceal gastrointestinal bleeding.BMC gastroenterology · 2020Article
- Guidelines for Nonvariceal Upper Gastrointestinal Bleeding.Gut and liver · 2020Review
- Outcomes of Upper Gastrointestinal Bleeding Based on Time to Endoscopy: A Retrospective Study.Cureus · 2020Article
- Predictors for the need for endoscopic therapy in patients with presumed acute upper gastrointestinal bleeding.The Korean journal of internal medicine · 2019Article
- Peptic Ulcer Is the Most Common Cause of Non-Variceal Upper-Gastrointestinal Bleeding (NVUGIB) in China.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Article
- Severity and Outcomes of Upper Gastrointestinal Bleeding With Bloody Vs. Coffee-Grounds Hematemesis.The American journal of gastroenterology · 2018Article
- Clinical implication of serum uric acid level in pegylated interferon and ribavirin combination therapy for chronic hepatitis C infection.The Korean journal of internal medicine · 2017Article
- Early esophagogastroduodenoscopy is associated with better Outcomes in upper gastrointestinal bleeding: a nationwide study.Endoscopy international open · 2017Article
- The Relationship between the Time of Endoscopy and Morbidity and Mortality Rates in Patients with Upper Gastrointestinal Bleeding.Advanced biomedical research · 2017Article
- Provision of out-of-hours services for acute upper gastrointestinal bleeding in England: results of the 2014-2015 BSG/NHS England national survey.Frontline gastroenterology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early endoscopy has been advocated for the management of upper gastrointestinal bleeding, but the optimal timing for early endoscopy is still uncertain. The aim of this Review is to evaluate the optimal timing of early endoscopy by examining the findings of randomized clinical trials and retrospective cohort studies that used comparable outcome measures and have been reported in the literature. Outcome measurements included recurrent bleeding, surgery, mortality, length of hospital stay, and blood transfusion. Studies were categorized into those in which endoscopy was performed within 2-3 h, 6-8 h, 12 h or 24 h of the patient's presentation to hospital. We conclude that early endoscopy aids risk stratification of patients and reduces the need for hospitalization. However, it may also expose additional cases of active bleeding and hence increase the use of therapeutic endoscopy. No evidence exists that very early endoscopy (within a few hours of presentation) can reduce the risk of rebleeding or improve survival.
Indexed as
Identifiers
19597510What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.