ArticlePediatrics2009
Mental health treatment patterns in perinatally HIV-infected youth and controls.
Article in Pediatrics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00100542 (Psychiatric Co-Morbidity in Perinatally HIV-Infected Children and Adolescents), which is not on this map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Psychiatric Co-Morbidity in Perinatally HIV-Infected Children and Adolescents
Who cites it
35 citing papers in PubMed, 66 citations in OpenAlex.
- Human immunodeficiency virus disease severity, psychiatric symptoms, and functional outcomes in perinatally infected youth.Archives of pediatrics & adolescent medicine · 2012Trial
- Psychosocial Factors Influencing the Sexual Risk Behaviour of Adolescents Living with and Affected by HIV Who Reside in HIV-Affected Homes in Uganda.AIDS and behavior · 2026Article
- Prevalence, Risk Factors, and Negative Outcomes of Anxiety and Depressive Disorders among HIV-Infected Children and Adolescents in Uganda: CHAKA Study 2014-2017.Psychiatry journal · 2022Article
- Observational
- Symptom Profiles of CD and ODD Among Youth With Perinatally Acquired HIV.Journal of pediatric psychology · 2020Article
- Coming of Age: Young Adults with Perinatally Acquired HIV Infection.Indian journal of pediatrics · 2019Article
- Agreement and Discrepancy on Emotional and Behavioral Problems Between Caregivers and HIV-Infected Children and Adolescents From Uganda.Frontiers in psychiatry · 2019Article
- Sertraline Pharmacokinetics in HIV-Infected and Uninfected Children, Adolescents, and Young Adults.Frontiers in pediatrics · 2019Article
- Mental Health Diagnoses, Symptoms, and Service Utilization in US Youth with Perinatal HIV Infection or HIV Exposure.AIDS patient care and STDs · 2019Article
- Assessing Psychiatric Symptoms in Youth Affected by HIV: Comparing a Brief Self-Administered Rating Scale with a Structured Diagnostic Interview.Journal of clinical psychology in medical settings · 2018Observational
- Anxiety and depression symptoms in young people with perinatally acquired HIV and HIV affected young people in England.AIDS care · 2018Article
- HIV treatment and care services for adolescents: a situational analysis of 218 facilities in 23 sub-Saharan African countries.Journal of the International AIDS Society · 2017Article
- A Prospective Longitudinal Study of Mental Health Symptoms Among Perinatally HIV-Infected and HIV-Exposed but Uninfected Urban Youths.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2016Article
- Resilience and Life Expectations of Perinatally HIV-1 Infected Adolescents in France.The open AIDS journal · 2016Article
- Changing Trends in Complications and Mortality Rates Among US Youth and Young Adults With HIV Infection in the Era of Combination Antiretroviral Therapy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015Article
- Sexual Health Knowledge in a Sample of Perinatally HIV-infected and Perinatally-exposed Uninfected Youth.Journal of HIV/AIDS & social services · 2015Article
- Psychiatric symptoms and antiretroviral nonadherence in US youth with perinatal HIV: a longitudinal study.AIDS (London, England) · 2015Article
- Substance use and the development of sexual risk behaviors in youth perinatally exposed to HIV.Journal of pediatric psychology · 2015Article
- Mental health and support among young key populations: an ecological approach to understanding and intervention.Journal of the International AIDS Society · 2015Article
- Getting to 90-90-90 in paediatric HIV: What is needed?Journal of the International AIDS Society · 2015Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
Abstract
backgroundYouths perinatally infected with HIV often receive psychotropic medication and behavioral treatment for emotional and behavioral symptoms. We describe patterns of intervention for HIV-positive youth and youth in a control group in the United States.
methodsThree hundred nineteen HIV-positive youth and 256 controls, aged 6 to 17 years, enrolled in the International Maternal Adolescent AIDS Clinical Trials 1055, a prospective, 2-year observational study of psychiatric symptoms. One hundred seventy-four youth in the control group were perinatally exposed to HIV, and 82 youth were uninfected children living in households with HIV-positive members. Youth and their primary caregivers completed Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition-referenced symptom-rating scales. Children's medication and behavioral psychiatric intervention histories were collected at entry. We evaluated the association of past or current psychiatric treatment with HIV status, baseline symptoms, and impairment by using multiple logistic regression, controlling for potential confounders.
resultsHIV-positive youth and youth in the control group had a similar prevalence of psychiatric symptoms (61%) and impairment (14% to 15%). One hundred four (18%) participants received psychotropic medications (stimulants [14%], antidepressants [6%], and neuroleptic agents [4%]), and 127 (22%) received behavioral treatment. More HIV-positive youth than youth in the control group received psychotropic medication (23% vs 12%) and behavioral treatment (27% vs 17%). After adjusting for symptom class and confounders, HIV-positive children had twice the odds of children in the control group of having received stimulants and >4 times the odds of having received antidepressants. Caregiver-reported symptoms or impairment were associated with higher odds of intervention than reports by children alone.
conclusionsHIV-positive children are more likely to receive mental health interventions than control-group children. Pediatricians and caregivers should consider available mental health treatment options for all children living in families affected by HIV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.