ArticleBJU international2010
Natural history of benign prostatic enlargement: long-term longitudinal population-based study of prostate volume doubling times.
Article in BJU international, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Patient-specific forecasting of postradiotherapy prostate-specific antigen kinetics enables early prediction of biochemical relapse.iScience · 2022Article
- Complications after surgery for benign prostatic enlargement: a population-based cohort study in Ontario, Canada.BMJ open · 2019Article
- Epidemiology and treatment modalities for the management of benign prostatic hyperplasia.Translational andrology and urology · 2019Review
- Mechanistic modelling of prostate-specific antigen dynamics shows potential for personalized prediction of radiation therapy outcome.Journal of the Royal Society, Interface · 2019Article
- Computer simulations suggest that prostate enlargement due to benign prostatic hyperplasia mechanically impedes prostate cancer growth.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Article
- Can men with prostates sized 80 mL or larger be managed conservatively?Investigative and clinical urology · 2017Article
- Landmarks in BPH--from aetiology to medical and surgical management.Nature reviews. Urology · 2014Review
- Article
- Associations between longitudinal changes in serum estrogen, testosterone, and bioavailable testosterone and changes in benign urologic outcomes.American journal of epidemiology · 2011Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectivesTo measure prostate volume doubling times (PVDTs) for a large sample of community men followed serially by transrectal ultrasonography (TRUS), and to determine whether specific characteristics are associated with a rapid PVDT. SUBJECTS AND
methodsA subsample of 446 subjects from a larger cohort of American white men aged 40-79 years were evaluated biennially for a median (range) follow-up of 10 (3-14) years. Mixed-effects regression models were used to estimate prostate growth rates and PVDT for subjects with three or more or with five or more serial biennial TRUS PV measurements.
resultsThe median (25-75th percentile) PVDT was 32.6 (24.6-44.0) years. The average annual increase in PV was 2.2%. The PVDT distribution was constant in men of all age groups studied (r < 0.001, P = 0.99). The factor most strongly associated with PVDT was baseline transition zone volume (r = -0.55, P < 0.001). Baseline total prostate-specific antigen (PSA) level, free PSA and total PV were also significantly inversely associated with PVDT (r = -0.30, -0.44 and -0.32, respectively, all P < 0.001). Age, baseline anthropomorphic measurements, hormone levels and specific lifestyle characteristics were not significantly correlated with PVDT.
conclusionThese data indicate that PVDT might be a useful future measure of benign prostatic growth. They provide a basis to forecast PV at 10, 20, or 30 years later, after one baseline TRUS measurement of prostate volume, and can be presented in a simple nomogram.
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