Evidence map›Paper›PMID 19593650›Full record

ArticleJournal of materials science. Materials in medicine2009

Biological properties of carbon/carbon implant composites with unique manufacturing processes.

Guo-Hui Wang, Shu Yu, Shai-Hong Zhu, Chang-Qing Gao, Yong Liu, Yun-Liang Miu, Bo-Yun Huang

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of materials science. Materials in medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 16 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Guo-Hui WangTransplantation Medical Academy, Third XiangYa Hospital, Central South University, Changsha, People's Republic of China.
Shu Yu
Shai-Hong Zhu
Chang-Qing Gao
Yong Liu
Yun-Liang Miu
Bo-Yun Huang
Central South University · CNTiandi Science & Technology (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal was to manufacture carbon/carbon (C/C) composites through a unique procedure with improved biocompatibility and reduced debris release. C/C composites were prepared by chemical vapor deposition, and their biological properties were analyzed. With regard to mechanical properties, compressive strength/modulus was 219.1 MPa/9.72 GPa, flexural strength/modulus was 121.63 MPa/21.9 GPa, and interlaminar sheer was 15.13 GPa. Biocompatibility testing revealed: (1) the extract liquid from the C/C composites had no effect on cell proliferation; (2) the extract had no impact on micronucleus frequency as compared with the control groups (P > 0.05); (3) in vivo, there was mild tissue inflammation after implantation within the first 2 weeks, but there was no significant difference compared with the control group (P > 0.05); (4) the implants were well integrated into the host tissue, and debris was limited. The tested samples have excellent biocompatibilities and reduced release of debris. The demonstrated changes in manufacturing procedures are promising.

Indexed as

Manufactured MaterialsAnimalsBiocompatible MaterialsCarbonCell LineFemaleFibroblastsFlow CytometryMaleMiceMicronucleus TestsRabbitsSkinBiocompatible MaterialsCarbon

Identifiers

PMID19593650
OpenAlexW1993128243

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.