Evidence map›Paper›PMID 19593546›Full record

ArticleIntensive care medicine2009

Tracking changes in cardiac output: methodological considerations for the validation of monitoring devices.

Pierre Squara, Maurizio Cecconi, Andrew Rhodes, Mervyn Singer, Jean-Daniel Chiche

Registry-linked trialAbstract read
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In one paragraph

Article in Intensive care medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03296319 (Echocardiography Guided Fluid Resuscitation in Critically Ill Patients), which is not on this map. Cited by 49 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03296319 nacompletednot on this mapstarted 2018, after this paper: background citation

Echocardiography Guided Fluid Resuscitation in Critically Ill Patients

TypeinterventionalSponsorAssiut UniversityRan2018 to 2020Enrolled120ConditionsFluid Responsiveness, EchocardiographyArmsEchocardiography
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  14. Goal-directed therapy: hit early and personalize!Journal of clinical monitoring and computing · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pierre SquaraRéanimation CERIC, Clinique Ambroise Paré, 27, Boulevard Victor Hugo, 92200, Neuilly, France.
Maurizio Cecconi
Andrew Rhodes
Mervyn Singer
Jean-Daniel Chiche

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUntil now, tools for continuous cardiac output (CO) monitoring have been validated as if they were tools for snapshot measurements. Most authors have compared variations in cardiac output between two time-points and used Bland-Altman representations to describe the agreement between these variations. The impacts of time and of repetitive measurements over time are not taken into consideration. PURPOSE: This special article proposes a conceptual framework for the validation of CO monitoring devices. Four quality criteria are suggested and studied: (1) accuracy (small bias), (2) precision (small random error of measurements), (3) short response time and (4) accurate amplitude response. Because a tolerance is obviously admitted for each of these four criteria, we propose to add as a fifth criterion the ability to detect significant CO directional changes. Other important issues in designing studies to validate CO monitoring tools are reviewed: choice of patient population to be studied, choice of the reference method, data acquisition method, data acceptability checking, data segmentation and final evaluation of reliability.

conclusionApplication of this framework underlines the importance of precision and time response for clinical acceptability of monitoring tools.

Indexed as

Cardiac OutputHeart Function TestsHumansValidation Studies as Topic

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.