Evidence map›Paper›PMID 19590885›Full record

ReviewChromosoma2009

At the right place at the right time: novel CENP-A binding proteins shed light on centromere assembly.

Mariana C C Silva, Lars E T Jansen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Chromosoma, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
8.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Depletion ofInternational journal of molecular sciences · 2019
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Temporal control of epigenetic centromere specification.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2012
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Centromere identity: a challenge to be faced.Molecular genetics and genomics : MGG · 2010
    Review
  17. Down the rabbit hole of centromere assembly and dynamics.Current opinion in cell biology · 2010
    Review
  18. Article
  19. Centromere identity, function, and epigenetic propagation across cell divisions.Cold Spring Harbor symposia on quantitative biology · 2010
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mariana C C SilvaLaboratory for Epigenetic Mechanisms, Instituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Lars E T Jansen
Instituto Gulbenkian de Ciência · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Centromeres, the chromosomal loci that form the sites of attachment for spindle microtubules during mitosis, are identified by a unique chromatin structure generated by nucleosomes containing the histone H3 variant CENP-A. The apparent epigenetic mode of centromere inheritance across mitotic and meiotic divisions has generated much interest in how CENP-A assembly occurs and how structurally divergent centromeric nucleosomes can specify the centromere complex. Although a substantial number of proteins have been implicated in centromere assembly, factors that can bind CENP-A specifically and deliver nascent protein to the centromere were, thus far, lacking. Several recent reports on experiments in fission yeast and human cells have now shown significant progress on this problem. Here, we discuss these new developments and their implications for epigenetic centromere inheritance.

Indexed as

Adaptor Proteins, Signal TransducingAnimalsAutoantigensCarrier ProteinsCell CycleCentromereCentromere Protein AChromatinChromosomal Proteins, Non-HistoneHumansSchizosaccharomyces pombe ProteinsAdaptor Proteins, Signal TransducingAutoantigensCarrier ProteinsCENPA protein, humanCentromere Protein AChromatinChromosomal Proteins, Non-HistoneMis16 protein, S pombeMIS18A protein, humanSchizosaccharomyces pombe ProteinsScm3 protein, S pombe

Identifiers

PMID19590885
OpenAlexW2012549607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.