ArticleEnvironmental health perspectives2009
Emergency admissions for cardiovascular and respiratory diseases and the chemical composition of fine particle air pollution.
Article in Environmental health perspectives, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 197 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
197 citing papers in PubMed, 7 syntheses or guidelines pooled it, 560 citations in OpenAlex.
- A State of the Science Review of Wildfire-Specific Fine Particulate Matter Data Sources, Methods, and Models.Environmental health perspectives · 2025Pooled it
- The association between ambient air pollution and migraine: a systematic review.Environmental monitoring and assessment · 2024Pooled it
- Pooled it
- A systematic review on global pollution status of particulate matter-associated potential toxic elements and health perspectives in urban environment.Environmental geochemistry and health · 2019Pooled it
- A systematic review of cardiovascular emergency department visits, hospital admissions and mortality associated with ambient black carbon.Environment international · 2017Pooled it
- A meta-analysis and multisite time-series analysis of the differential toxicity of major fine particulate matter constituents.American journal of epidemiology · 2012Pooled it
- Black carbon as an additional indicator of the adverse health effects of airborne particles compared with PM10 and PM2.5.Environmental health perspectives · 2011Pooled it
- Effect of Portable Air Filtration Systems on Personal Exposure to Fine Particulate Matter and Blood Pressure Among Residents in a Low-Income Senior Facility: A Randomized Clinical Trial.JAMA internal medicine · 2018Trial
- Short-term diesel exhaust inhalation in a controlled human crossover study is associated with changes in DNA methylation of circulating mononuclear cells in asthmatics.Particle and fibre toxicology · 2014Trial
- MicroRNA expression in response to controlled exposure to diesel exhaust: attenuation by the antioxidant N-acetylcysteine in a randomized crossover study.Environmental health perspectives · 2013Trial
- Composition of PM affects acute vascular inflammatory and coagulative markers - the RAPTES project.PloS one · 2013Trial
- Applying Satellite-Derived PMGeoHealth · 2026Article
- Association between wildfire smoke exposure and pediatric emergency department visits for headache.Headache · 2026Article
- The importance of investigating temporal variability in short-term effects of air pollution on mortality at the local level: a 12-year study in a high-risk Italian area.BMC public health · 2026Article
- PMEnvironment & health (Washington, D.C.) · 2026Article
- New approaches to uncover COPD pathobiology and develop therapies.JCI insight · 2026Review
- Association of PMRespiratory research · 2026Article
- The association between long-term exposure to PMChemosphere · 2025Article
- Hospital admissions attributable to reduced air pollution due to clean-air policies in China.Nature medicine · 2025Article
- Effect of the S100A9/AMPK pathway on PM2.5-mediated mouse lung injury.Iranian journal of basic medical sciences · 2025Article
137 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPopulation-based studies have estimated health risks of short-term exposure to fine particles using mass of PM(2.5) (particulate matter <or= 2.5 microm in aerodynamic diameter) as the indicator. Evidence regarding the toxicity of the chemical components of the PM(2.5) mixture is limited.
objectiveIn this study we investigated the association between hospital admission for cardiovascular disease (CVD) and respiratory disease and the chemical components of PM(2.5) in the United States.
methodsWe used a national database comprising daily data for 2000-2006 on emergency hospital admissions for cardiovascular and respiratory outcomes, ambient levels of major PM(2.5) chemical components [sulfate, nitrate, silicon, elemental carbon (EC), organic carbon matter (OCM), and sodium and ammonium ions], and weather. Using Bayesian hierarchical statistical models, we estimated the associations between daily levels of PM(2.5) components and risk of hospital admissions in 119 U.S. urban communities for 12 million Medicare enrollees (>or= 65 years of age).
resultsIn multiple-pollutant models that adjust for the levels of other pollutants, an interquartile range (IQR) increase in EC was associated with a 0.80% [95% posterior interval (PI), 0.34-1.27%] increase in risk of same-day cardiovascular admissions, and an IQR increase in OCM was associated with a 1.01% (95% PI, 0.04-1.98%) increase in risk of respiratory admissions on the same day. Other components were not associated with cardiovascular or respiratory hospital admissions in multiple-pollutant models.
conclusionsAmbient levels of EC and OCM, which are generated primarily from vehicle emissions, diesel, and wood burning, were associated with the largest risks of emergency hospitalization across the major chemical constituents of PM(2.5).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.