ArticleBMC genomics2009
Hmrbase: a database of hormones and their receptors.
Article in BMC genomics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Contemporary data-driven innovations in peptide-based therapeutic design.Briefings in bioinformatics · 2026Review
- The Role of Metabolites in Cell-Cell Communication: A Review of Databases and Computational Tools.Cells · 2025Review
- CellPhoneDB v5: inferring cell-cell communication from single-cell multiomics data.Nature protocols · 2025Review
- A comprehensive dataset of therapeutic peptides on multi-function property and structure information.Scientific data · 2025Article
- Milk-Derived Antimicrobial Peptides: Overview, Applications, and Future Perspectives.Probiotics and antimicrobial proteins · 2023Review
- Predicting cross-tissue hormone-gene relations using balanced word embeddings.Bioinformatics (Oxford, England) · 2022Article
- HORDB a comprehensive database of peptide hormones.Scientific data · 2022Article
- Multivariable regulation of gene expression plasticity in metazoans.Open biology · 2019Article
- Article
- SpirPep: an in silico digestion-based platform to assist bioactive peptides discovery from a genome-wide database.BMC bioinformatics · 2018Article
- Prediction of Antimicrobial Potential of a Chemically Modified Peptide From Its Tertiary Structure.Frontiers in microbiology · 2018Article
- SATPdb: a database of structurally annotated therapeutic peptides.Nucleic acids research · 2016Article
- EndoNet: an information resource about the intercellular signaling network.BMC systems biology · 2014Article
- metabolicMine: an integrated genomics, genetics and proteomics data warehouse for common metabolic disease research.Database : the journal of biological databases and curation · 2013Article
- TumorHoPe: a database of tumor homing peptides.PloS one · 2012Article
- PepX: a structural database of non-redundant protein-peptide complexes.Nucleic acids research · 2010Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHormones are signaling molecules that play vital roles in various life processes, like growth and differentiation, physiology, and reproduction. These molecules are mostly secreted by endocrine glands, and transported to target organs through the bloodstream. Deficient, or excessive, levels of hormones are associated with several diseases such as cancer, osteoporosis, diabetes etc. Thus, it is important to collect and compile information about hormones and their receptors. DESCRIPTION: This manuscript describes a database called Hmrbase which has been developed for managing information about hormones and their receptors. It is a highly curated database for which information has been collected from the literature and the public databases. The current version of Hmrbase contains comprehensive information about approximately 2000 hormones, e.g., about their function, source organism, receptors, mature sequences, structures etc. Hmrbase also contains information about approximately 3000 hormone receptors, in terms of amino acid sequences, subcellular localizations, ligands, and post-translational modifications etc. One of the major features of this database is that it provides data about approximately 4100 hormone-receptor pairs. A number of online tools have been integrated into the database, to provide the facilities like keyword search, structure-based search, mapping of a given peptide(s) on the hormone/receptor sequence, sequence similarity search. This database also provides a number of external links to other resources/databases in order to help in the retrieving of further related information.
conclusionOwing to the high impact of endocrine research in the biomedical sciences, the Hmrbase could become a leading data portal for researchers. The salient features of Hmrbase are hormone-receptor pair-related information, mapping of peptide stretches on the protein sequences of hormones and receptors, Pfam domain annotations, categorical browsing options, online data submission, DrugPedia linkage etc. Hmrbase is available online for public from http://crdd.osdd.net/raghava/hmrbase/.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.