Evidence map›Paper›PMID 19587829›Full record

ArticleJournal of oncology2009

Estimation of Cachexia among Cancer Patients Based on Four Definitions.

Kathleen M Fox, John M Brooks, Shravanthi R Gandra, Richard Markus, Chiun-Fang Chiou

Registry-linked trialAbstract read
In one paragraph

Article in Journal of oncology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03245658 (The Effect of Medical Cannabis Inpatients With Palliative Pancreatic Cancer), which is not on this map. Cited by 72 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03245658 phase2withdrawnnot on this mapstarted 2017, after this paper: background citation

The Effect of Medical Cannabis Inpatients With Palliative Pancreatic Cancer

TypeinterventionalSponsorJens Rikardt AndersenRan2017 to 2018Enrolled0ConditionsNeoplasms Pancreatic, Cachexia, Cancer, CannabisArmsTHC and CBD Mixture
3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  19. Role of noncoding RNAs in pancreatic ductal adenocarcinoma associated cachexia.American journal of physiology. Cell physiology · 2022
    Review
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kathleen M FoxStrategic Healthcare Solutions, LLC, P.O. Box 543, Monkton, MD 21111, USA.
John M Brooks
Shravanthi R Gandra
Richard Markus
Chiun-Fang Chiou

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives. Estimate and compare the proportion of cancer patients with cachexia using different definitions from available clinical data. Methods. Electronic medical records were examined to estimate the proportion of cancer patients with cachexia using 4 definitions: (1) ICD-9 diagnostic code of 799.4 (cachexia), (2) ICD-9 diagnosis of cachexia, anorexia, abnormal weight loss, or feeding difficulties, (3) prescription for megestrol acetate, oxandrolone, somatropin, or dronabinol, and (4) >/=5% weight loss. Patients with cancer of the stomach, pancreas, lung, colon/rectum, head/neck, esophagus, prostate, breast, or liver diagnosed between 1999 and 2004 were followed for cachexia. Results. Of 8541 cancer patients (60% men and 55% Caucasian), cachexia was observed in 2.4% of patients using the cachexia diagnostic code, 5.5% expanded diagnoses, 6.4% prescription medication definition, and 14.7% with >/=5% weight loss. Conclusions. The proportion of patients with cachexia varied considerably depending upon the definition employed, indicating that a standard operational definition is needed.

Identifiers

PMID19587829
PMCPMC2705834

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.