Evidence map›Paper›PMID 19586941›Full record

ReviewHaematologica2009

Genetic and immune-related factors in the pathogenesis of lymphoproliferative and plasma cell malignancies.

Sigurdur Y Kristinsson, Lynn R Goldin, Magnus Björkholm, Jill Koshiol, Ingemar Turesson, Ola Landgren

Open access · goldAbstract readReview
In one paragraph

Review in Haematologica, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  10. Cancer incidence in Canada: trends and projections (1983-2032).Health promotion and chronic disease prevention in Canada : research, policy and practice · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sigurdur Y KristinssonDepartment of Medicine, Division of Hematology, Karolinska University Hospital Solna and Karolinska Institutet, Stockholm, Sweden.
Lynn R Goldin
Magnus Björkholm
Jill Koshiol
Ingemar Turesson
Ola Landgren
Karolinska University Hospital · SELund University · SE

Funding

Molecular and clinical profilingZIABC011352 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LANDGREN, OLA · 2010 to 2014
$4.4M
Intramural NIH HHS
6 · The paper itself

Abstract

There are data to support a role for genetic and immune-related factors in the pathogenesis of lymphomas and plasma cell diseases. In this paper, we review our published large population-based studies and other relevant studies in Hodgkin's and non-Hodgkin's lymphomas, multiple myeloma, and the precursor condition monoclonal gammopathy of undetermined significance. We discuss the overlap in risk factors between related malignancies and explore the underlying mechanisms. Based on these studies, we provide clinical implications and discuss the relevance of these data for patient counseling and clinical follow-up. Finally, we suggest future directions for new studies designed to increase our current knowledge and to define underlying biological mechanisms of our findings.

Indexed as

HumansLymphomaLymphoproliferative DisordersMultiple MyelomaNeoplasms, Plasma CellParaproteinemiasRisk Factors

Identifiers

PMID19586941
PMCPMC2770969
OpenAlexW2158955930

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.