Evidence map›Paper›PMID 19584824›Full record

ArticleBone marrow transplantation2010

Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe 2009.

P Ljungman, M Bregni, M Brune, J Cornelissen, T de Witte, G Dini, H Einsele, H B Gaspar, A Gratwohl, J Passweg and 9 more

Registry-linked trialOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Bone marrow transplantation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01034449 (Transplantation of Ex-vivo Expanded Human Cord Blood Hematopoietic Stem Cells Expanded), which is not on this map. Cited by 103 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 4 pooled it
17.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01034449 phase2completednot on this map

Transplantation of Ex-vivo Expanded Human Cord Blood Hematopoietic Stem Cells Expanded: Evaluation of Hematopoietic and Immunologic Reconstitution After a Reduced-intensity Conditioning Regimen

TypeinterventionalSponsorUniversity Hospital, BordeauxRan2010 to 2014Enrolled16ConditionsMalignant Haematological DiseaseArmsallogeneic transplant
3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 4 syntheses or guidelines pooled it, 384 citations in OpenAlex.

  1. Prognostic value of sarcopenia in survivors of hematological malignances undergoing a hematopoietic stem cell transplantation: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Pooled it
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  3. Guideline
  4. Pooled it
  5. Article
  6. Review
  7. Article
  8. Article
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  11. Bone Marrow Grafts From Pediatric Donors May Contain A Considerable Number of Hematogones.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2022
    Article
  12. Article
  13. Molecular Mechanisms and Therapies of Myeloid Leukaemia.International journal of molecular sciences · 2022
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  15. Article
  16. Review
  17. Article
  18. Article
  19. Metabolic Pathways in Alloreactive T Cells.Frontiers in immunology · 2020
    Review
  20. Review

43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 16 institutions in 8 countries.

P LjungmanDepartment of Haematology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden. Per.Ljungman@ki.se
M Bregni
M Brune
J Cornelissen
T de Witte
G Dini
H Einsele
H B Gaspar
A Gratwohl
J Passweg
C Peters
V Rocha
R Saccardi
H Schouten
A Sureda
A Tichelli
A Velardi
D Niederwieser
European Group for Blood and Marrow Transplantation
University Hospital of Basel · CHErasmus MC Cancer Institute · NLHospital de Sant Pau · ESIstituto Giannina Gaslini · ITKarolinska University Hospital · SELeipzig University · DEMaastricht University Medical Centre · NLOspedale San Giuseppe · ITRadboud University Medical Center · NLSahlgrenska University Hospital · SESt Anna Children's Hospital · ATUniversity College London · GBUniversity Hospital of Geneva · CHUniversity of Florence · ITUniversity of Perugia · ITUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The European Group for Blood and Marrow Transplantation regularly publishes special reports on the current practice of haematopoietic SCT for haematological diseases, solid tumours and immune disorders in Europe. Major changes have occurred since the first report was published. HSCT today includes grafting with allogeneic and autologous stem cells derived from BM, peripheral blood and cord blood. With reduced-intensity conditioning regimens in allogeneic transplantation, the age limit has increased, permitting the inclusion of older patients. New indications have emerged, such as autoimmune disorders and AL amyloidosis for autologous HSCT and solid tumours, myeloproliferative syndromes and specific subgroups of lymphomas for allogeneic transplants. The introduction of alternative therapies, such as imatinib for CML, has challenged well-established indications. An updated report with revised tables and operating definitions is presented.

Indexed as

Hematopoietic Stem Cell TransplantationAdolescentAdultAgedAmyloidosisBone Marrow TransplantationChildClinical ProtocolsEuropeHematologic DiseasesHodgkin DiseaseHumansImmune System DiseasesInfantLeukemiaLymphoma, Non-Hodgkin

Identifiers

PMID19584824
OpenAlexW2136575529

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.