ArticleBMC infectious diseases2009
Inactivation of murine norovirus by chemical biocides on stainless steel.
Article in BMC infectious diseases, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 59 citations in OpenAlex.
- Process Technologies for Disinfection of Food-Contact Surfaces in the Dry Food Industry: A Review.Microorganisms · 2025Review
- Review
- Impact of Theaflavins-Enriched Tea Leaf Extract TY-1 against Surrogate Viruses of Human Norovirus: In Vitro Virucidal Study.Pathogens (Basel, Switzerland) · 2022Article
- Efficacy of an alcohol-based surface disinfectant formulation against human norovirus.Journal of applied microbiology · 2022Article
- Inactivation of Murine Norovirus Suspended in Organic Matter Simulating Actual Conditions of Viral Contamination.Food and environmental virology · 2021Article
- Bactericidal and virucidal activity of ethanol and povidone-iodine.MicrobiologyOpen · 2020Review
- Resistance of Enteric Viruses on Fomites.Intervirology · 2018Review
- Quantitative Risk Assessment of Norovirus Transmission in Food Establishments: Evaluating the Impact of Intervention Strategies and Food Employee Behavior on the Risk Associated with Norovirus in Foods.Risk analysis : an official publication of the Society for Risk Analysis · 2017Article
- Virucidal Efficacy of a Hydrogen Peroxide Nebulization Against Murine Norovirus and Feline Calicivirus, Two Surrogates of Human Norovirus.Food and environmental virology · 2016Article
- Development and virucidal activity of a novel alcohol-based hand disinfectant supplemented with urea and citric acid.BMC infectious diseases · 2016Article
- Study of the virucidal potential of organic peroxyacids against norovirus on food-contact surfaces.Food and environmental virology · 2015Article
- Surface-Dried Viruses Can Resist Glucoprotamin-Based Disinfection.Applied and environmental microbiology · 2014Article
- Prevention of contamination by xenotropic murine leukemia virus-related virus: susceptibility to alcohol-based disinfectants and environmental stability.Applied and environmental microbiology · 2014Article
- Article
- A broadly reactive one-step SYBR Green I real-time RT-PCR assay for rapid detection of murine norovirus.PloS one · 2014Article
- Impact of Sodium Chloride, Sucrose and Milk on Heat Stability of the Murine Norovirus and the MS2 Phage.Food and environmental virology · 2013Article
- Inactivation of an enterovirus by airborne disinfectants.BMC infectious diseases · 2013Article
- Inactivation of caliciviruses.Pharmaceuticals (Basel, Switzerland) · 2013Article
- Critical review of norovirus surrogates in food safety research: rationale for considering volunteer studies.Food and environmental virology · 2012Review
- Comparison of the Activity of Alcohol-Based Handrubs Against Human Noroviruses Using the Fingerpad Method and Quantitative Real-Time PCR.Food and environmental virology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHuman norovirus (NoV) causes more than 80% of nonbacterial gastroenteritis in Europe and the United States. NoV transmission via contaminated surfaces may be significant for the spread of viruses. Therefore, measures for prevention and control, such as surface disinfection, are necessary to interrupt the dissemination of human NoV. Murine norovirus (MNV) as a surrogate for human NoV was used to study the efficacy of active ingredients of chemical disinfectants for virus inactivation on inanimate surfaces.
methodsThe inactivating properties of different chemical biocides were tested in a quantitative carrier test with stainless steel discs without mechanical action. Vacuum-dried MNV was exposed to different concentrations of alcohols, peracetic acid (PAA) or glutaraldehyde (GDA) for 5 minutes exposure time. Detection of residual virus was determined by endpoint-titration on RAW 264.7 cells.
resultsPAA [1000 ppm], GDA [2500 ppm], ethanol [50% (v/v)] and 1-propanol [30% (v/v)] were able to inactivate MNV under clean conditions (0.03% BSA) on the carriers by > or = 4 log10 within 5 minutes exposure time, whereas 2-propanol showed a reduced effectiveness even at 60% (v/v). Furthermore, there were no significant differences in virus reduction whatever interfering substances were used. When testing with ethanol, 1- and 2-propanol, results under clean conditions were nearly the same as in the presence of dirty conditions (0.3% BSA plus 0.3% erythrocytes).
conclusionProducts based upon PAA, GDA, ethanol and 1-propanol should be used for NoV inactivation on inanimate surfaces. Our data provide valuable information for the development of strategies to control NoV transmission via surfaces.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.