ArticleJournal of fluorescence2010
Elucidating anomalous protein diffusion in living cells with fluorescence correlation spectroscopy-facts and pitfalls.
Article in Journal of fluorescence, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Universal kinetics of imperfect reactions in confinement.Communications chemistry · 2021Article
- Biological physics by high-speed atomic force microscopy.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2020Review
- Variations in Plasma Membrane Topography Can Explain Heterogenous Diffusion Coefficients Obtained by Fluorescence Correlation Spectroscopy.Frontiers in cell and developmental biology · 2020Article
- HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb.Biophysical journal · 2019Article
- Out of the Randomness: Correlating Noise in Biological Systems.Biophysical journal · 2018Review
- Measurement of Rapid Protein Diffusion in the Cytoplasm by Photo-Converted Intensity Profile Expansion.Cell reports · 2017Article
- Poisson pre-processing of nonstationary photonic signals: Signals with equality between mean and variance.PloS one · 2017Article
- Inferring diffusion dynamics from FCS in heterogeneous nuclear environments.Biophysical journal · 2015Article
- Protein Simulations in Fluids: Coupling the OPEP Coarse-Grained Force Field with Hydrodynamics.Journal of chemical theory and computation · 2015Article
- Article
- Computer Simulations of the Bacterial Cytoplasm.Biophysical reviews · 2013Article
- The shape of protein crowders is a major determinant of protein diffusion.Biophysical journal · 2013Article
- Unraveling transcription factor interactions with heterochromatin protein 1 using fluorescence lifetime imaging microscopy and fluorescence correlation spectroscopy.Journal of biomedical optics · 2013Article
- A quantitative model of ERK MAP kinase phosphorylation in crowded media.Scientific reports · 2013Article
- Wanted: a positive control for anomalous subdiffusion.Biophysical journal · 2012Review
- Anomalous diffusion of brain metabolites evidenced by diffusion-weighted magnetic resonance spectroscopy in vivo.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2012Article
- Resolving a paradox of anomalous scalings in the diffusion of granular materials.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Localization and dynamics of nuclear speckles in plants.Plant physiology · 2012Review
- Article
- Physiological environment induces quick response - slow exhaustion reactions.Frontiers in physiology · 2011Article
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Authors and funding
2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Anomalous protein diffusion has been frequently observed in intracellular fluids and on membranes of living cells. Indeed, a large variety of specimen, from bacteriae to mammalian cells, and several non-invasive measurement techniques, e.g. fluorescence correlation spectroscopy, have revealed that the mean square displacement (MSD) of proteins in vivo is often characterized by an anomalous power-law increase mean value of tau(t)(2) mean value of ~ t(alpha) with 0.5 < alpha </= 0.8. Here, we review these results with a particular focus on fluorescence correlation spectroscopy, and we report on possible causes of variations of the anomaly degree alpha. Moreover, we highlight generic consequences of anomalous diffusion that are likely to play an important role in the cellular context.
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