ArticlePediatric nephrology (Berlin, Germany)2009
Outcome and management of isolated moderate renal pelvis dilatation detected at postnatal screening.
Article in Pediatric nephrology (Berlin, Germany), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 29 citations in OpenAlex.
- The Diagnostic Efficacy of and Requirement for Postnatal Ultrasonography Screening for Congenital Anomalies of the Kidney and Urinary Tract.Diagnostics (Basel, Switzerland) · 2023Article
- The association between continuous antibiotic prophylaxis and UTI from birth until initial postnatal imaging evaluation among newborns with antenatal hydronephrosis.Journal of pediatric urology · 2018Article
- Article
- Ultrasonography of hydronephrosis in the newborn: a practical review.Ultrasonography (Seoul, Korea) · 2016Review
- From Research Question to Conducting a Randomized Controlled Trial on Continuous Antibiotic Prophylaxis in Prenatal Hydronephrosis: A Rational Stepwise Process.Frontiers in pediatrics · 2016Article
- Diagnostic accuracy of neonatal kidney ultrasound in children having antenatal hydronephrosis without ureter and bladder abnormalities.World journal of urology · 2015Article
- Children and adolescents with ureteropelvic junction obstruction: is an additional voiding cystourethrogram necessary? Results of a multicenter study.World journal of urology · 2013Article
- Clinical importance of pyelocalyceal dilation diagnosed by postnatal ultrasonographic screening of the urinary tract.Medical science monitor : international medical journal of experimental and clinical research · 2013Article
- Natural history of bilateral mild isolated antenatal hydronephrosis conservatively managed.Pediatric nephrology (Berlin, Germany) · 2012Article
- Antibiotic prophylaxis in antenatal nonrefluxing hydronephrosis, megaureter and ureterocele.Nature reviews. Urology · 2012Review
- Probability of urinary tract infection in infants with ureteropelvic junction obstruction: is antibacterial prophylaxis really needed?Pediatric nephrology (Berlin, Germany) · 2011Article
- Outcome and management of isolated severe renal pelvis dilatation detected at postnatal screening.Pediatric nephrology (Berlin, Germany) · 2010Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to evaluate the incidence and outcome of isolated moderate renal pelvis dilatation (RPD) [anterior-posterior diameter (APD) 10-15 mm] in an unselected population of 2-month-old infants prospectively followed for up to 12-14 months of life. Isolated moderate renal pelvis dilatation was detected in 282 of the 11,801 (2.4%), infants screened; 240 infants with normal renal ultrasound were enrolled as the control group. Resolution of RPD was considered when an APD <or= 5 mm was found on two consecutive sonograms. Urological investigations were initiated if the RPD persisted or if urinary tract infection (UTI) occurred during follow-up, and antibiotic therapy was administered only when UTI occurred. The events of interest were resolution of the RPD, presence of uropathy and UTI. At follow-up, RPD persisted only in 18 infants; of these, four infants were diagnosed with vesicoureteral reflux (grade 1-3) and 14 with ureteropelvic junction obstruction. Of the 223 infants with RPD and 230 control infants who completed follow-up, UTI occurred in 3.6 and 2.5%, respectively. The incidence rate of UTI per 1000 person-months was 5.98 episodes in the patient group and 5.22 episodes in the control group. The rate ratio was 1.146 (95% confidence interval 0.389-3.54, p = 0.8). Our data suggest that isolated moderate RPD is essentially a self-limiting condition and that antibiotic prophylaxis for the prevention of UTI should not be performed. A non-invasive ultrasound scan performed during the follow-up is sufficient to diagnose a potentially dangerous and persistent RPD.
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