SynthesisJOP : Journal of the pancreas2009
Alcohol as a risk factor for pancreatitis. A systematic review and meta-analysis.
Synthesis in JOP : Journal of the pancreas, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
78 citing papers in PubMed, 10 syntheses or guidelines pooled it, 194 citations in OpenAlex.
- AEG-AESPANC-OPGE-SIED-SPG Ibero-Latin American Guidelines on Acute Pancreatitis (iLATAM-AP).United European gastroenterology journal · 2026Guideline
- The impact of COVID-19 lockdown on snacking habits, fast-food and alcohol consumption: A systematic review of the evidence.Clinical nutrition (Edinburgh, Scotland) · 2022Pooled it
- Proposing a "Brain Health Checkup (BHC)" as a Global Potential "Standard of Care" to Overcome Reward Dysregulation in Primary Care Medicine: Coupling Genetic Risk Testing and Induction of "Dopamine Homeostasis".International journal of environmental research and public health · 2022Pooled it
- Role of the CommonGenes · 2020Pooled it
- Coexistence of alcohol-related pancreatitis and alcohol-related liver disease: A systematic review and meta-analysis.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2020Pooled it
- The relationship between different dimensions of alcohol use and the burden of disease-an update.Addiction (Abingdon, England) · 2017Pooled it
- Dietary Patterns and Pancreatic Cancer Risk: A Meta-Analysis.Nutrients · 2017Pooled it
- Alcohol Consumption as a Risk Factor for Acute and Chronic Pancreatitis: A Systematic Review and a Series of Meta-analyses.EBioMedicine · 2015Pooled it
- Factors associated with dengue shock syndrome: a systematic review and meta-analysis.PLoS neglected tropical diseases · 2013Pooled it
- Dose-risk and duration-risk relationships between aspirin and colorectal cancer: a meta-analysis of published cohort studies.PloS one · 2013Pooled it
- Assessing the burden and trends of pancreatitis in India from 1990-2021: An analysis of the global burden of disease database.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- The Increasing Disease Burden Among Males and the Elderly in Pancreatitis: Latest Insights from the 2021 Global Burden of Disease Study.Digestive diseases and sciences · 2026Article
- Treatment Strategies for Chronic Pancreatitis (CP).Pharmaceuticals (Basel, Switzerland) · 2025Review
- Article
- Multiple substance use and the risk of pancreatitis: a systematic review.Therapeutic advances in gastroenterology · 2025Review
- Turkish Society of Gastroenterology: Pancreas Working Group, Acute Pancreatitis Committee Consensus Report.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024Review
- Research hotspots and frontiers of alcohol and epilepsy: A bibliometric analysis.Neuropsychopharmacology reports · 2024Review
- Global, regional, and national burden of pancreatitis in older adults, 1990-2019: A systematic analysis for the global burden of disease study 2019.Preventive medicine reports · 2024Article
- Acute Pancreatitis: Clinical Profile of 60 Patients.Cureus · 2023Article
- The Impact of the COVID-19 Pandemic on Outcomes in Acute Pancreatitis: A Propensity Score Matched Study Comparing before and during the Pandemic.Diagnostics (Basel, Switzerland) · 2023Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
contextEpidemiologic studies have suggested an association between alcohol consumption and pancreatitis, although the exact dose-response relationship is unknown. It also remains uncertain whether a threshold effect exists.
objectiveTo conduct a systematic review and meta-analysis of epidemiologic studies on the association between alcohol consumption and the risk of pancreatitis.
methodsWe searched Ovid MEDLINE, EMBASE, CINAHL, Web of Science, ETOH and AIM. Studies were included if they reported quantifiable information on risk and related confidence intervals with respect to at least three different levels of alcohol intake.
resultsSix studies, including 146,517 individuals with 1,671 cases of pancreatitis, met the inclusion criteria. We found a monotonic and approximately exponential dose-response relationship between average volume of alcohol consumption and pancreatitis. However, in a categorical analysis the lower drinking categories were not significantly elevated, with an apparent threshold of 4 drinks daily.
conclusionsAs the available evidence also indicates that the relationship is biologically plausible, these results support the existence of a link between alcohol consumption and the risk of pancreatitis.
Indexed as
Identifiers
19581740PMC3299482W2105497827What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.