ArticleJournal of bacteriology2009
Structure of compositionally simple lipopolysaccharide from marine synechococcus.
Article in Journal of bacteriology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 71 citations in OpenAlex.
- Anoxia-adapted cyanobacteria in a marine blue hole.Applied and environmental microbiology · 2026Article
- Conserved tripartite tail proteins mediate virophage-host interactions throughJournal of virology · 2025Article
- In Vivo Biocompatibility ofJournal of functional biomaterials · 2024Article
- The role of the protective shield against UV-C radiation and its molecular interactions in Nostoc species (Cyanobacteria).Scientific reports · 2024Article
- Biomedical engineering utilizing living photosynthetic cyanobacteria and microalgae: Current status and future prospects.Materials today. Bio · 2024Review
- Cyanobacterial harmful bloom lipopolysaccharides: pro-inflammatory effects on epithelial and immune cells in vitro.Archives of toxicology · 2024Article
- Proteome trait regulation of marine Synechococcus elemental stoichiometry under global change.The ISME journal · 2024Article
- Cyanotoxins, biosynthetic gene clusters, and factors modulating cyanotoxin biosynthesis.World journal of microbiology & biotechnology · 2023Review
- Future ocean conditions induce necrosis, microbial dysbiosis and nutrient cycling imbalance in the reef sponge Stylissa flabelliformis.ISME communications · 2023Article
- Article
- Novel functional insights into a modified sugar-binding protein from Synechococcus MITS9220.Scientific reports · 2022Article
- Article
- Review
- Regulation Mechanism Mediated byFrontiers in microbiology · 2018Article
- Lipid A structural modifications in extreme conditions and identification of unique modifying enzymes to define the Toll-like receptor 4 structure-activity relationship.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2017Review
- Mutations in Novel Lipopolysaccharide Biogenesis Genes Confer Resistance to Amoebal Grazing in Synechococcus elongatus.Applied and environmental microbiology · 2016Article
- Classical and Alternative Activation of Cyanobacterium Oscillatoria sp. Lipopolysaccharide-Treated Rat Microglia in vitro.Toxicological sciences : an official journal of the Society of Toxicology · 2016Article
- Metagenomic Analysis Reveals Symbiotic Relationship among Bacteria in Microcystis-Dominated Community.Frontiers in microbiology · 2016Article
- Slr2019, lipid A transporter homolog, is essential for acidic tolerance in Synechocystis sp. PCC6803.Photosynthesis research · 2015Article
- Structure and Effects of Cyanobacterial Lipopolysaccharides.Marine drugs · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lipopolysaccharide (LPS) is the first defense against changing environmental factors for many bacteria. Here, we report the first structure of the LPS from cyanobacteria based on two strains of marine Synechococcus, WH8102 and CC9311. While enteric LPS contains some of the most complex carbohydrate residues in nature, the full-length versions of these cyanobacterial LPSs have neither heptose nor 3-deoxy-D-manno-octulosonic acid (Kdo) but instead 4-linked glucose as their main saccharide component, with low levels of glucosamine and galacturonic acid also present. Matrix-assisted laser desorption ionization mass spectrometry of the intact minimal core LPS reveals triacylated and tetraacylated structures having a heterogeneous mix of both hydroxylated and nonhydroxylated fatty acids connected to the diglucosamine backbone and a predominantly glucose outer core-like region for both strains. WH8102 incorporated rhamnose in this region as well, contributing to differences in sugar composition and possibly nutritional differences between the strains. In contrast to enteric lipid A, which can be liberated from LPS by mild acid hydrolysis, lipid A from these organisms could be produced by only two novel procedures: triethylamine-assisted periodate oxidation and acetolysis. The lipid A contains odd-chain hydroxylated fatty acids, lacks phosphate, and contains a single galacturonic acid. The LPS lacks any limulus amoebocyte lysate gelation activity. The highly simplified nature of LPSs from these organisms leads us to believe that they may represent either a primordial structure or an adaptation to the relatively higher salt and potentially growth-limiting phosphate levels in marine environments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.