Evidence map›Paper›PMID 19581360›Full record

ArticleJournal of bacteriology2009

Staphylococcus aureus YoeB homologues inhibit translation initiation.

Satoshi Yoshizumi, Yonglong Zhang, Yoshihiro Yamaguchi, Liang Chen, Barry N Kreiswirth, Masayori Inouye

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 54 citations in OpenAlex.

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  5. Frontiers in microbiology · 2021
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  17. Defining the mRNA recognition signature of a bacterial toxin protein.Proceedings of the National Academy of Sciences of the United States of America · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Satoshi YoshizumiDepartment of Biochemistry, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA.
Yonglong Zhang
Yoshihiro Yamaguchi
Liang Chen
Barry N Kreiswirth
Masayori Inouye
Johnson University · USInternational Center for Public Health · US

Funding

Deciphering of the Toxin-Antitoxin Systems in E. coliR01GM081567 · NIGMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI INOUYE, MASAYORI · 2009 to 2012
$1.8M
NIGMS NIH HHS 1R01GM081567-01A2NIGMS NIH HHS R01 GM081567
6 · The paper itself

Abstract

YoeB is a bacterial toxin encoded by the yefM-yoeB toxin-antitoxin system found in various bacterial genomes. Here, we show that Staphylococcus aureus contains two YoeB homologues, both of which function as ribosome-dependent mRNA interferases to inhibit translation initiation in a manner identical to that of YoeB-ec from Escherichia coli.

Indexed as

Sequence Homology, Amino AcidAmino Acid SequenceBacterial ProteinsBacterial ToxinsEscherichia coli ProteinsHumansMolecular Sequence DataPeptide Chain Initiation, TranslationalProtein Synthesis InhibitorsSequence AlignmentStaphylococcus aureusBacterial ProteinsBacterial ToxinsEscherichia coli ProteinsProtein Synthesis InhibitorsYefM protein, E coliYoeB protein, E coli

Identifiers

PMID19581360
PMCPMC2737954
OpenAlexW2147540328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.