Evidence map›Paper›PMID 19578977›Full record

ArticleMolecular biology reports2010

Identification and expression analysis of two zebrafish E2F5 genes during oogenesis and development.

Qiwen Yang, Jiarui Hu, Ding Ye, Cailian Zhao, Shan Song, Wuming Gong, Zheng Tan, Ping Song

Abstract read
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In one paragraph

Article in Molecular biology reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Large Yellow Croaker (International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Qiwen YangCollege of Life Science, Wuhan University, 430072, Wuhan, Hubei, China.
Jiarui Hu
Ding Ye
Cailian Zhao
Shan Song
Wuming Gong
Zheng Tan
Ping Song
Wuhan University · CNHubei University · CNHuazhong Agricultural University · CNOhio Wesleyan University · USZhongnan Hospital of Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the process of screening genes that are preferentially expressed in zebrafish germ cells, we isolated an E2F family member zE2F5b, which is a truncated isoform of zebrafish E2F5a. The E2F transcription factors are thought to play an essential role in cell cycle progression. Reverse transcription polymerase chain reaction and whole mount in situ hybridization analyses have demonstrated that both zE2F5a and zE2F5b mRNAs are predominantly expressed in stage I and II oocytes. In early development, the two zE2F5 transcripts are expressed by many parts of the embryo and are then restricted to the brain area. Interestingly, zE2F5b mRNA is detected later in the lens and optic tectum while zE2F5a mRNA is absent. Our data suggests that E2F5 may play important roles in zebrafish brain, eye and ovarian development.

Indexed as

Gene Expression ProfilingGene Expression Regulation, DevelopmentalAmino Acid SequenceAnimalsE2F5 Transcription FactorEmbryo, NonmammalianExonsFemaleIntronsMolecular Sequence DataOocytesOogenesisOvaryPhylogenyProtein Structure, TertiaryRNA, MessengerE2F5 Transcription FactorRNA, MessengerZebrafish Proteins

Identifiers

PMID19578977
OpenAlexW2001529036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.