Evidence map›Paper›PMID 19578806›Full record

ArticleActa neurochirurgica2010

Primary brain T-cell lymphoma of the lymphoblastic type presenting as altered mental status.

Aaron J Clark, Kangmin Lee, William C Broaddus, Mary Jo Martin, Nitya R Ghatak, Catherine E Grossman, Sherman Baker, Ahmet Baykal

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Acta neurochirurgica, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Primary peripheral T-cell central nervous system lymphoma.Surgical neurology international · 2021
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Aaron J ClarkDeparment of Neurosurgery, Virginia Commonwealth University Medical Center, Richmond, VA, USA. Aaron.Clark@ucsfmedctr.org
Kangmin Lee
William C Broaddus
Mary Jo Martin
Nitya R Ghatak
Catherine E Grossman
Sherman Baker
Ahmet Baykal
Virginia Commonwealth University Medical Center · USUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The authors present a case of a 56-year-old man with altered mental status. Magnetic resonance imaging (MRI) of the brain revealed non-enhancing abnormalities on T2 and FLAIR imaging in the brainstem, cerebellum, and cerebrum. Immunohistochemisty demonstrated precursor T-cell lymphoblastic lymphoma. After treatment with methotrexate, he improved clinically without focal sensorimotor deficits and with improving orientation. MRI showed almost complete resolution of brainstem and cerebral lesions. To the authors' knowledge, there are only five previous reports of primary central nervous system T-cell lymphoblastic lymphoma. Since treatable, it deserves consideration in patients with altered mental status and imaging abnormalities that include diffuse, non-enhancing changes with increased signal on T2-weighted images.

Indexed as

Antimetabolites, AntineoplasticBiopsyBrain NeoplasmsHumansImmunohistochemistryInjections, IntravenousInjections, SpinalMagnetic Resonance ImagingMaleMental DisordersMethotrexateMiddle AgedPrecursor T-Cell Lymphoblastic Leukemia-LymphomaAntimetabolites, AntineoplasticMethotrexate

Identifiers

PMID19578806
PMCPMC2801848
OpenAlexW2118651490

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.