Evidence map›Paper›PMID 19578658›Full record

ArticleClinics (Sao Paulo, Brazil)2009

Long-term surgical outcomes of primary congenital glaucoma in China.

Xiulan Zhang, Shaolin Du, Qian Fan, Shouxiong Peng, Minbin Yu, Jian Ge

Open access · goldAbstract readComparative Study
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. The efficacy of adjunctive mitomycin C and/or anti-VEGF agents on glaucoma tube shunt drainage device surgeries: a systematic review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Pooled it
  2. Surgical interventions for primary congenital glaucoma.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Surgical interventions for primary congenital glaucoma.The Cochrane database of systematic reviews · 2015
    Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Progression in pediatric glaucoma: lessons learnt from 8 years' follow-up.Medical hypothesis, discovery & innovation ophthalmology journal · 2021
    Article
  11. Article
  12. Article
  13. Observational
  14. Combined trabeculotomy-trabeculectomy using the modified Safer Surgery System augmented with MMC: its long-term outcomes of glaucoma treatment in Asian children.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018
    Article
  15. Article
  16. Article
  17. Article
  18. Surgical management of glaucoma: evolving paradigms.Indian journal of ophthalmology · 2011
    Review
  19. Review
  20. Primary congenital glaucoma: An updated review.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiulan ZhangGlaucoma Department, Zhongshan Ophthalmic Centre, State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangzhou, China.
Shaolin Du
Qian Fan
Shouxiong Peng
Minbin Yu
Jian Ge
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the long-term outcomes of three surgical procedures for the treatment of primary congenital glaucoma (PCG).

introductionPCG is one of the main causes of blindness in children. There is a paucity of contemporary data on PCG in China.

methodsA retrospective study of 48 patients (81 eyes) with PCG who underwent primary trabeculectomy, trabeculotomy, or combined trabeculotomy and trabeculectomy (CTT).

resultsAll patients were less than 4 years (yrs) of age, with a mean age of 2.08 +/- 1.23 yrs. The mean duration of follow-up was 5.49 +/- 3.09 yrs. The difference in success rates among the three surgical procedures at 1, 3, 6 and 9 yrs was not statistically significant (p = 0.492). However, in patients with over 4 yrs of follow-up, Kaplan-Meier survival analysis revealed that the success rates of trabeculectomy and CTT declined more slowly than that of trabeculotomy. Among the patients, 66.22% acquired good vision (VA > 0.4), 17.57% acquired fair vision (VA = 0.1 - 0.3), and 16.22% acquired poor vision (VA < 0.1). The patients with good vision were mostly in the successful surgery group. Myopia was more prevalent postoperatively (p = 0.009). Reductions in the cup-disc ratio and corneal diameter were only seen in the successful surgery group (p = 0.000). In addition, the successful surgery group contained more patients that complied with a regular follow-up routine (p = 0.002). DISCUSSION: Our cases were all primary surgeries. Primary trabeculectomy was performed in many cases because no treatment was sought until an advanced stage of disease had been reached.

conclusionsIn contrast to most reports, in the present study, trabeculectomy and CTT achieved higher long-term success rates than trabeculotomy. The patients with successful surgical results had better vision. Compliance with a routine of regular follow-up may increase the chances of a successful surgical outcome.

Indexed as

ChildChild, PreschoolChinaEpidemiologic MethodsGlaucomaHumansInfantIntraocular PressureLong-Term CareTrabeculectomyTreatment OutcomeChinaCombined trabeculotomy and trabeculectomy (CTT)Primary congenital glaucoma (PCG)TrabeculectomyTrabeculotomy

Identifiers

PMID19578658
PMCPMC2705148
OpenAlexW1975632392

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.