ReviewNature reviews. Neurology2009
Critical illness polyneuropathy and myopathy in the intensive care unit.
Review in Nature reviews. Neurology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 117 citations in OpenAlex.
- Guillain-Barré syndrome spectrum associated with COVID-19: an up-to-date systematic review of 73 cases.Journal of neurology · 2021Pooled it
- Early treatment with IgM-enriched intravenous immunoglobulin does not mitigate critical illness polyneuropathy and/or myopathy in patients with multiple organ failure and SIRS/sepsis: a prospective, randomized, placebo-controlled, double-blinded trial.Critical care (London, England) · 2013Trial
- Neurophysiology and muscle histopathology in ICU-acquired muscle weakness: Lessons learned from COVID-19.Clinical neurophysiology practice · 2025Article
- Early detection of low QRS voltage and its association with mortality in patients with sepsis.Scientific reports · 2024Article
- Patterns of Unwanted Biological and Technical Expression Variation Among 49 Human Tissues.Laboratory investigation; a journal of technical methods and pathology · 2024Article
- Lower serum cholesterol levels as a risk factor for critical illness polyneuropathy: a matched case-control study.Scientific reports · 2023Article
- Prevalence and prognostic value of neurological affections in hospitalized patients with moderate to severe COVID-19 based on objective assessments.Scientific reports · 2023Article
- Perceived barriers to mobility in the intensive care units of Singapore: The Patient Mobilisation Attitudes and Beliefs Survey for the intensive care units.Journal of the Intensive Care Society · 2023Article
- THE EFFECT OF IN-BED LEG CYCLING EXERCISES ON MUSCLE STRENGTH IN PATIENTS WITH INTENSIVE CARE UNIT-ACQUIRED WEAKNESS: A SINGLE-CENTER RETROSPECTIVE STUDY.Journal of rehabilitation medicine. Clinical communications · 2023Article
- Feasibility of Muscle Endurance Testing in Critically Ill Trauma Patients: A Pilot Study.Healthcare (Basel, Switzerland) · 2022Article
- Early detection of ICU-acquired weakness in septic shock patients ventilated longer than 72 h.BMC pulmonary medicine · 2022Article
- A First View of the Effect of a Trial of Early Mobilization on the Muscle Strength and Activities of Daily Living in Mechanically Ventilated Patients With COVID-19.Archives of rehabilitation research and clinical translation · 2022Article
- Sepsis-associated neuroinflammation in the spinal cord.PloS one · 2022Article
- High-dose intravenous immunoglobulins as a therapeutic option in critical illness polyneuropathy accompanying SARS-CoV-2 infection: A case-based review of the literature (Review).Experimental and therapeutic medicine · 2021Review
- Association Between SARS-CoV-2 Infection and Immune-Mediated Myopathy in Patients Who Have Died.JAMA neurology · 2021Article
- ATTR amyloidosis during the COVID-19 pandemic: insights from a global medical roundtable.Orphanet journal of rare diseases · 2021Article
- Mid-German Sepsis Cohort (MSC): a prospective observational study of sepsis survivorship.BMJ open · 2021Observational
- Intensive Care and Treatment of Severe Guillain-Barré Syndrome.Frontiers in pharmacology · 2021Review
- Article
- Predictors of Major Depressive Disorder following Intensive Care of Chronically Critically Ill Patients.Critical care research and practice · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Critical illness polyneuropathy (CIP) and critical illness myopathy (CIM) are major complications that occur in severely ill patients who require intensive care treatment. CIP and CIM affect the limb and respiratory muscles, and, as a consequence, they characteristically complicate weaning from the ventilator, increase the length of stay on the intensive care unit, and prolong physical rehabilitation. The basic pathophysiology of both disorders is complex and involves metabolic, inflammatory and bioenergetic alterations. It is unclear at present whether CIP and CIM are distinct entities, or whether they just represent different 'organ' manifestations of a common pathophysiological mechanism. This article provides an overview of the clinical and diagnostic features of CIP and CIM and discusses current pathophysiological and therapeutic concepts relating to these neuromuscular disorders.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.