ArticleThe Journal of allergy and clinical immunology2009
Major increase in allergic sensitization in schoolchildren from 1996 to 2006 in northern Sweden.
Article in The Journal of allergy and clinical immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
73 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Effect of prenatal indoor pet exposure on the trajectory of total IgE levels in early childhood.The Journal of allergy and clinical immunology · 2011Trial
- Common Food Emulsifiers Impair Epithelial Barrier Integrity and Trigger Pro-Inflammatory Responses and IgE Production.Allergy · 2026Article
- Reported Symptoms Upon Exposure to Aeroallergen Highly Predict Allergen Sensitization Among 12-Year-Old Children.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Association between Allergy Symptoms upon Pet Exposure and Sensitization to Dog and Cat Allergen Molecules in Teenagers.International archives of allergy and immunology · 2026Article
- Taming pet allergens: strategies to make furry cats less allergenic.Frontiers in allergy · 2026Review
- Exposure to vehicle traffic in childhood and lung function in young adulthood-a prospective cohort study in an area with low traffic-flows.Environmental health : a global access science source · 2025Article
- Allergic rhinitis: Incidence and remission from childhood to young adulthood-A prospective study.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Article
- Tropomyosin-based cross-reactivity and asymptomatic shellfish sensitization in patients with perennial allergy.Frontiers in allergy · 2025Article
- Worsening asthma at school is associated with poor psychosocial well-being.European clinical respiratory journal · 2025Article
- Fel d 1 specific IgE measurement for dog exclusive owners co-sensitized to dog and cat.The World Allergy Organization journal · 2024Article
- Diagnostic intervention improved health-related quality of life among teenagers with food allergy.PloS one · 2024Article
- Prevalence and risk factors for allergic sensitization: 3 cross-sectional studies among schoolchildren from 1996 to 2017.The journal of allergy and clinical immunology. Global · 2023Article
- Sensitization patterns to cat molecular allergens in subjects with allergic sensitization to cat dander.Clinical and translational allergy · 2023Article
- Sensitization to molecular dog allergens in an adult population: Results from the West Sweden Asthma Study.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2023Article
- Determinants of uncontrolled allergic rhinitis in Kinshasa hospitals.Frontiers in allergy · 2023Article
- The association between specific IgE antibodies to component allergens and allergic symptoms on dog and cat exposure among Korean pet exhibition participants.The World Allergy Organization journal · 2022Article
- Early-life risk factors for development of asthma from 8 to 28 years of age: a prospective cohort study.ERJ open research · 2022Article
- Allergic sensitization to lipocalins reflects asthma morbidity in dog dander sensitized children.Clinical and translational allergy · 2022Article
- Sensitization to Furry Animals in Patients with Suspected Allergic Disease in China: A Multicenter Study.Journal of asthma and allergy · 2022Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundTime trends for allergic sensitization are poorly known.
objectiveTo compare the trends in prevalence of allergic sensitization and associated risk factors in children.
methodsTwo cohorts of children (age 7-8 years) were invited for skin prick tests (SPTs) 10 years apart, 1996 and 2006. The participation rates were 2148 (88%) and 1700 (90%), respectively. The methods were identical, and 10 common airborne allergens were used. An expanded International Study of Allergy and Asthma in Children questionnaire about symptoms and possible risk factors for allergic conditions was completed by the parents.
resultsThe prevalence of any positive SPT increased from 21% in 1996 to 30% in 2006 (P < .001). The pattern of sensitization remained similar, and sensitization to cat was most common both years, 13% and 19%, respectively. Sensitization to mites and mold was uncommon in both surveys. A family history of allergy was a significant risk factor for a positive SPT both years (odds ratio, 1.7). Factors that in 1996 had a protective effect, such as rural living and having several siblings, had lost this effect in 2006. The prevalence of most risk factors remained similar, but respiratory infections and smoking among parents decreased significantly. During the same period, there was no significant increase in the prevalence of current wheeze (11.9% to 12.4%, P = .636) or symptoms of rhinitis or eczema.
conclusionThe prevalence of allergic sensitization increased significantly from 1996 to 2006, whereas no increase in clinical symptoms was found. The parallel decrease in parental smoking and respiratory infections indicate a different influence of environmental factors on allergic sensitization and clinical symptoms, respectively.
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