Evidence map›Paper›PMID 19575491›Full record

ArticleWorld journal of gastroenterology2009

Microscopic colitis: a large retrospective analysis from a health maintenance organization experience.

Kevin-T Kao, Benito-A Pedraza, Amy-C McClune, David-A Rios, Yi-Qiong Mao, Robert-H Zuch, Michael-H Kanter, Sony Wirio, Chris-N Conteas

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03063957 (Identification and Characterization of Microbial and Immunologic Changes in Microscopic Colitis), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03063957 unknown statusnot on this mapstarted 2015, after this paper: background citation

Identification and Characterization of Microbial and Immunologic Changes in Microscopic Colitis

TypeobservationalSponsorMassachusetts General HospitalRan2015 to 2024Enrolled330ConditionsColitis, Microscopic
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Controversials of Microscopic Colitis.Frontiers in medicine · 2021
    Review
  10. Review
  11. Increased Mast Cell Counts and Degranulation in Microscopic Colitis.Gastroenterology research and practice · 2020
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Necessary additional points.Deutsches Arzteblatt international · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Kevin-T KaoDepartment of Gastroenterology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA 90027, USA. kevin.t.kao@kp.org
Benito-A Pedraza
Amy-C McClune
David-A Rios
Yi-Qiong Mao
Robert-H Zuch
Michael-H Kanter
Sony Wirio
Chris-N Conteas
Los Angeles Medical Center · USKaiser Permanente · USSan Raffaele University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo examine the demographic data on a large multi-ethnic population of patients with microscopic colitis (MC) in Southern California and to determine the association of MC with inflammatory bowel disease (IBD) and colorectal cancer.

methodsAll patients diagnosed with MC by colonic biopsy from 1996-2005 were identified utilizing a pathology database. All biopsies were reviewed by experienced pathologists utilizing standard histologic criteria. Patients' medical records were reviewed and data regarding patient age, co-morbidities, sex, ethnicity, and medications were analyzed. An age- and sex-matched standard control group was also generated. Chi-square test was used to evaluate the associations of co-morbidities between lymphocytic colitis (LC), collagenous colitis (CC) and the control group.

resultsA total of 547 cases of MC were identified, 376 patients with LC and 171 patients with CC. The female/male ratio was 3:1 in CC and 2.7:1 in LC patients. Celiac disease (P < 0.001), irritable bowel syndrome (IBS) (P < 0.001), and thyroid diseases (P < 0.001) were found to have a higher occurrence in MC compared to the control group. No statistical differences in the occurrence of colorectal cancer, diabetes and IBD were found between the MC group and the control group.

conclusionThis is the largest group of patients with MC known to the authors that has been studied to date. Conditions such as celiac disease, IBS, and thyroid diseases were found to be related to MC. Furthermore, neither an increased risk of colorectal cancer nor IBD was associated with MC in this study.

Indexed as

Colitis, MicroscopicAdultAgedAged, 80 and overCaliforniaColorectal NeoplasmsComorbidityDatabases, FactualEthnicityFemaleHumansInflammatory Bowel DiseasesMaleMiddle AgedRetrospective StudiesYoung Adult

Identifiers

PMID19575491
PMCPMC2705734
OpenAlexW1995281812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.