ArticleInternational urology and nephrology2009
Does glomerular hyperfiltration in pregnancy damage the kidney in women with more parities?
Article in International urology and nephrology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed.
- Adverse pregnancy outcomes are associated with cardiovascular and renal dysregulation in late pregnancy.BMC pregnancy and childbirth · 2026Article
- Pregnancy after Kidney Transplantation-Impact of Functional Renal Reserve, Slope of eGFR before Pregnancy, and Intensity of Immunosuppression on Kidney Function and Maternal Health.Journal of clinical medicine · 2023Article
- Glomerular hyperfiltration.Nature reviews. Nephrology · 2022Review
- Association of Glomerular Hyperfiltration and Cardiovascular Risk in Middle-Aged Healthy Individuals.JAMA network open · 2020Article
- Pregnancy Is a Risk Factor for Secondary Focal Segmental Glomerulosclerosis in Women with a History of Very Low Birth Weight.Internal medicine (Tokyo, Japan) · 2017Article
- The renal circulation in normal pregnancy and preeclampsia: is there a place for relaxin?American journal of physiology. Renal physiology · 2014Review
- Glomerular hyperfiltration: definitions, mechanisms and clinical implications.Nature reviews. Nephrology · 2012Review
- Intensifying renal replacement therapy during pregnancy: the role for nocturnal home hemodialysis.International urology and nephrology · 2010Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe aimed to investigate the glomerular hyperfiltration due to pregnancy in women with more parities.
methodsFive hundred women aged 52.57 +/- 8.08 years, without a history of hypertension, diabetes mellitus or complicated pregnancy were involved in the study. They were divided into three groups. Group 1: women with no or one parity (n = 76); group 2: women with two or three parities (n = 333); group 3: women with four or more parities (n = 91). Laboratory parameters and demographical data were compared between the three groups.
resultsMean age, serum urea and serum creatinine were similar between three groups. Patients in group 3 had significantly higher GFR values compared to groups 1 and 2 (109.44 +/- 30.99, 110.76 +/- 30.22 and 121.92 +/- 34.73 mL/min/1.73 m(2) for groups 1, 2 and 3, respectively; P = 0.008 for group 1 vs group 3; P = 0.002 for group 2 vs group 3).
conclusionsIn our study, we suggest that glomerular hyperfiltration due to pregnancy does not have adverse effects on kidney in women with more parities. Pregnancy may have possible protective mechanisms for kidney against adverse effects of glomerular hyperfiltration.
Indexed as
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Registered trials
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